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Ehjcardiovascrec

[...]Sp mice exhibited increased atrial ectopy and susceptibility to pacing-induced AF, both of which were also prevented by the RyR2 S2814A mutation. Previously, studies have found that protein ...

Cardiovascular Research, Chiang, David Y., Li, Na, Wang, Qiongling, Alsina, Katherina M., Quick, Ann P., Reynolds, Julia O., Wang, Guoliang, Skapura, Darlene, Voigt, Niels, Dobrev, Dobromir, Wehrens, ...

Date : 01/07/2014
Ehjcardiovascrec

The potential relevance of increased incidence of spontaneous SR Ca2+ release for both AF induction and/or maintenance and the development of novel mechanism-based therapeutic approaches will be ...

Cardiovascular Research, Dobrev, Dobromir, Voigt, Niels, Wehrens, Xander H.T.

Date : 01/03/2011 Item size : 490642 bytes
Ehjcardiovascrec

Loss of this function by mutations or down-regulation of protein expression has been linked to hypertrophic cardiomyopathy, arrhythmias, and progression of disease in failing hearts. Within the ...

Cardiovascular Research, Beavers, David L., Landstrom, Andrew P., Chiang, David Y., Wehrens, Xander H.T.

Date : 15/07/2014 Item size : 432063 bytes
Ehjcardiovascrec

Methods and results Using a novel cardiac-specific short-hairpin-RNA-mediated JPH2 knockdown mouse model (Mus musculus; αMHC-shJPH2), we assessed the effects of the loss of JPH2 on the maturation ...

Cardiovascular Research, Reynolds, Julia O., Chiang, David Y., Wang, Wei, Beavers, David L., Dixit, Sayali S., Skapura, Darlene G., Landstrom, Andrew P., Song, Long-Sheng, Ackerman, Michael J., ...

Date : 01/10/2013 Item size : 296128 bytes
Ehjcardiovascrec

[...]it has become clear that the clinical factors predisposing to AF and the cellular and molecular mechanisms involved are extremely complex. [...]all AF-promoting and maintaining mechanisms are ...

Cardiovascular Research, Heijman, Jordi, Algalarrondo, Vincent, Voigt, Niels, Melka, Jonathan, Wehrens, Xander H.T., Dobrev, Dobromir, Nattel, Stanley

Date : 01/04/2016 Item size : 643880 bytes
Ehjcardiovascrec

The pathogenesis of atrial fibrillation (AF), the most common sustained cardiac arrhythmia, involves multiple factors including dysfunction of a variety of ion channels, dysregulation of calcium ...

Cardiovascular Research, Li, Na, Dobrev, Dobromir, Wehrens, Xander H.T.

Date : 01/03/2016 Item size : 180376 bytes
Ehjcardiovascrec

[...]Sp mice exhibited increased atrial ectopy and susceptibility to pacing-induced AF, both of which were also prevented by the RyR2 S2814A mutation. Previously, studies have found that protein ...

Cardiovascular Research, Chiang, David Y., Li, Na, Wang, Qiongling, Alsina, Katherina M., Quick, Ann P., Reynolds, Julia O., Wang, Guoliang, Skapura, Darlene, Voigt, Niels, Dobrev, Dobromir, Wehrens, ...

Date : 01/07/2014 Item size : 341722 bytes
Ehjcardiovascrec

The pathogenesis of atrial fibrillation (AF), the most common sustained cardiac arrhythmia, involves multiple factors including dysfunction of a variety of ion channels, dysregulation of calcium ...

Cardiovascular Research, Li, Na, Dobrev, Dobromir, Wehrens, Xander H.T.

Date : 01/03/2016 Item size : 184183 bytes
Ehjcardiovascrec

[...]it has become clear that the clinical factors predisposing to AF and the cellular and molecular mechanisms involved are extremely complex. [...]all AF-promoting and maintaining mechanisms are ...

Cardiovascular Research, Heijman, Jordi, Algalarrondo, Vincent, Voigt, Niels, Melka, Jonathan, Wehrens, Xander H.T., Dobrev, Dobromir, Nattel, Stanley

Date : 01/04/2016 Item size : 629318 bytes