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Ehjcardiovascrec

Conclusion: Data show that SR Ca2+ release and SR Ca2+ content were increased in hypertrophied myocytes, despite an increase in the steady state INa/Ca density. The observation that increased SR ...

Cardiovascular Research, Original Article, Alzbeta Chorvatova, George Hart, Munir Hussain

Date : 01/02/2004 Item size : 266773 bytes
Ehjcardiovascrec

Norepinephrine released by the sympathetic nerves in the heart and epinephrine released into the circulation by adrenal glands increase myocardial contractility by acting on both α- and ...

Cardiovascular Research, Review, Jean-Luc Balligand

Date : 15/08/1999 Item size : 527441 bytes
Ehjcardiovascrec

Abstract Objective: Our aims were: (1) to examine the effect of pH (7.46.5) on Ca2+release from the sarcoplasmic reticulum (SR) of cardiac muscle, and (2) to see if these effects were altered by ...

Cardiovascular Research, Original Article, Jonathan C Kentish, Jian-Zhong Xiang

Date : 01/02/1997 Item size : 206551 bytes
Ehjcardiovascrec

[...]altered expression of PLB and SLN has been reported in many cardiac diseases. [...]SERCA2a is a major regulator of intracellular Ca2+ homeostasis, and changes in the expression and activity of ...

Cardiovascular Research, Review, Muthu Periasamy, Poornima Bhupathy, Gopal J. Babu

Date : 15/01/2008 Item size : 520644 bytes
Ehjcardiovascrec

Abstract Objective: The aim was to determine whether myofilament Ca2+ sensitivity is altered in skinned cardiac fibres from endotoxin-treated rabbits. Methods: Endotoxin was injected i.v. in ...

Cardiovascular Research, Original Article, Benoı̂t Tavernier, Delphine Garrigue, Claire Boulle, Benoı̂t Vallet, Pascal Adnet

Date : 01/05/1998
Ehjcardiovascrec

Abstract Objective: In heart failure, little information is available as to the Ca2+ release function of sarcoplasmic reticulum (SR), which plays a major role in cardiac contractile function. Here, ...

Cardiovascular Research, Original Article, Takeshi Yamamoto, Masafumi Yano, Michihiro Kohno, Takayuki Hisaoka, Kaoru Ono, Taketo Tanigawa, Yukio Saiki, Yuhji Hisamatsu, Tomoko Ohkusa, Masunori ...

Date : 01/10/1999
Ehjcardiovascrec

Methods and results We measured NADPH oxidase activity, RyR2 S-glutathionylation, and calcium release kinetics in sarcoplasmic reticulum (SR) vesicles isolated from dog ventricular muscle after ...

Cardiovascular Research, Original Article, Gina Sánchez, Matías Escobar, Zully Pedrozo, Pilar Macho, Raúl Domenech, Steffen Härtel, Cecilia Hidalgo, Paulina Donoso

Date : 15/01/2008
Ehjcardiovascrec

More than a century ago, Traube noted that patients with severe congestive heart failure tend to have alternating strong and weak pulses, or pulsus alternans [8]. [...]mechanical restitution, a ...

Cardiovascular Research, Review, Ronald M Phillips, Prakash Narayan, Ana M Gómez, Keith Dilly, Larry R Jones, W.Jonathan Lederer, Ruth A Altschuld

Date : 01/02/1998
Ehjcardiovascrec

Introduction In the heart, triadin and junctin are two specialized proteins that link the Ca2+-buffering protein calsequestrin (Casq2) to the sarcoplasmic reticulum (SR) ryanodine receptor ...

Cardiovascular Research, SPOTLIGHT REVIEWS: SPOTLIGHT ON T-TUBULES AND RYANODINE RECEPTOR MICRODOMAIN SIGNALLING IN CARDIAC HYPERTROPHY AND FAILURE, Nagesh Chopra, Björn C. Knollmann

Date : 01/05/2013
Ehjcardiovascrec

In this study, we tested the hypothesis that SLN is a regulator of SR Ca2+ transport function by overexpressing SLN in adult rat ventricular myocytes which express low levels of SLN. In smaller ...

Cardiovascular Research, Research Article, Gopal J. Babu, Zhaolun Zheng, Poornima Natarajan, Debra Wheeler, Paul M. Janssen, Muthu Periasamy

Date : 01/01/2005