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Ehjcardiovascrec

KeywordsHistidine-rich Ca-binding proteinTransgenicIschemia/reperfusionApoptosisCa cycling Time for primary review 20 days This article is referred to in the Editorial by Tanno and Miura (pages ...

Cardiovascular Research, Original Article, Xiaoyang Zhou, Guo-Chang Fan, Xiaoping Ren, Jason R. Waggoner, Kimberly N. Gregory, Guoli Chen, W. Keith Jones, Evangelia G. Kranias

Date : 01/08/2007 Item size : 300437 bytes
Ehjcardiovascrec

Abstract Aims It has been shown that sarcoplasmic reticulum calcium ATPase (SERCA) plays a critical role in reperfusion injury. [...]ischaemic post-conditioning (PoCo) results in protein kinase G ...

Cardiovascular Research, Cardiac biology and remodelling, Javier Inserte, Víctor Hernando, Marisol Ruiz-Meana, Marcos Poncelas-Nozal, Celia Fernández, Luis Agulló, Carmem Sartorio, Úrsula ...

Date : 01/09/2014 Item size : 366352 bytes
Ehjcardiovascrec

Introduction In patients with ST-segment elevation acute myocardial infarction (AMI), the main therapeutic goal is to restore coronary flow as soon as possible by means of percutaneous intervention ...

Cardiovascular Research, Review, Javier Inserte, José A. Barrabés, Víctor Hernando, David Garcia-Dorado

Date : 15/07/2009 Item size : 489326 bytes
Ehjcardiovascrec

[...]deregulated calpain activity has been associated with a variety of pathophysiological conditions which have in common the loss of intracellular Ca2+ control.1 A large amount of experimental data ...

Cardiovascular Research, REVIEWS: FOCUS ON THE CALPAIN FAMILY IN THE CARDIOVASCULAR SYSTEM, Javier Inserte, Victor Hernando, David Garcia-Dorado

Date : 01/10/2012 Item size : 559929 bytes
Ehjcardiovascrec

[...]the so-called Ca2+ paradox (hypercontracture and death of cardiomyocytes occurring upon restoration of Ca2+ after a Ca2+-free perfusion period) was meant to be a first cellular model of ...

Cardiovascular Research, REVIEWS: SPOTLIGHT ON REDUCING MYOCARDIAL ISCHAEMIA/REPERFUSION INJURY, David Garcia-Dorado, Marisol Ruiz-Meana, Javier Inserte, Antonio Rodriguez-Sinovas, Hans Michael Piper

Date : 01/05/2012
Ehjcardiovascrec

[9] (pages 326333) in this issue. 1 Altered ion homeostasis during ischemia: critical role of intracellular Ca2+ overload Ischemic heart diseases still constitute the leading cause of mortality and ...

Cardiovascular Research, Editorial, Kanigula Mubagwa

Date : 01/02/2002
Ehjcardiovascrec

In view of the role of sarcoplasmic reticulum Ca-cycling in myocardial ischemia/reperfusion injury, we designed this study to gain further insight into the role of HRC during ...

Cardiovascular Research, Zhou, Xiaoyang, Fan, Guo-Chang, Ren, Xiaoping, Waggoner, Jason R., Gregory, Kimberly N., Chen, Guoli, Jones, W. Keith, Kranias, Evangelia G.

Date : 01/08/2007 Item size : 297396 bytes
Ehjcardiovascrec

Purpose: Myocardial ischaemia-reperfusion injury (IRI) is characterised by excessive intracellular levels of Ca2+ in cardiomyocytes which leads to mitochondrial pore opening and cell death. Ned-19 ...

Cardiovascular Research, Foote, KK, Zhao, YJ, Graeff, RM, Yellon, DM, Davidson, SM

Date : 15/07/2014 Item size : 97598 bytes
Ehjcardiovascrec

[...]the so-called Ca2+ paradox (hypercontracture and death of cardiomyocytes occurring upon restoration of Ca2+ after a Ca2+-free perfusion period) was meant to be a first cellular model of ...

Cardiovascular Research, Garcia-Dorado, David, Ruiz-Meana, Marisol, Inserte, Javier, Rodriguez-Sinovas, Antonio, Piper, Hans Michael

Date : 01/05/2012 Item size : 742256 bytes
Ehjcardiovascrec

Research on the mechanisms leading to sarcolemmal rupture and necrosis during initial reperfusion identified several promising pharmacological targets directed either to correct the alterations in ...

Cardiovascular Research, Inserte, Javier, Barrabés, José A., Hernando, Víctor, Garcia-Dorado, David

Date : 15/07/2009 Item size : 459107 bytes