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Ehjcardiovascrec

Abstract Objective: The aim was to determine whether myofilament Ca2+ sensitivity is altered in skinned cardiac fibres from endotoxin-treated rabbits. Methods: Endotoxin was injected i.v. in ...

Cardiovascular Research, Original Article, Benoı̂t Tavernier, Delphine Garrigue, Claire Boulle, Benoı̂t Vallet, Pascal Adnet

Date : 01/05/1998
Ehjcardiovascrec

Abstract Objective: In heart failure, little information is available as to the Ca2+ release function of sarcoplasmic reticulum (SR), which plays a major role in cardiac contractile function. Here, ...

Cardiovascular Research, Original Article, Takeshi Yamamoto, Masafumi Yano, Michihiro Kohno, Takayuki Hisaoka, Kaoru Ono, Taketo Tanigawa, Yukio Saiki, Yuhji Hisamatsu, Tomoko Ohkusa, Masunori ...

Date : 01/10/1999
Ehjcardiovascrec

The apparent affinity of CaM for RyR2 was considerably lower in failing sarcoplasmic reticulum (SR) compared with normal SR. [...]the amount of CaM bound to RyR2 was markedly decreased in failing ...

Cardiovascular Research, Original Article, Akihiro Hino, Masafumi Yano, Takayoshi Kato, Masakazu Fukuda, Takeshi Suetomi, Makoto Ono, Wakako Murakami, Takehisa Susa, Shinichi Okuda, Masahiro Doi, ...

Date : 01/12/2012
Ehjcardiovascrec

In a variety of pathological situations, contractile function may also be influenced by inducible NOS (iNOS) expressed in several cell types, including infiltrating inflammatory cells, coronary ...

Cardiovascular Research, Review, Walter J Paulus, Ajay M Shah

Date : 15/08/1999
Ehjcardiovascrec

Abstract Objective:The immunosuppressive drug Cyclosporine A (CsA) is a key substance in pharmacological therapy following solid organ transplantation and has been suggested to prevent cardiac ...

Cardiovascular Research, Original Article, Paul M.L Janssen, Oliver Zeitz, Boris Keweloh, Ulf Siegel, Lars S Maier, Paul Barckhausen, Burkert Pieske, Jürgen Prestle, Stephan E Lehnart, Gerd ...

Date : 01/07/2000
Ehjcardiovascrec

Abstract Objective: Prolonged cardiac contraction and relaxation in hypothyroidism are in part related to diminished expression of the gene coding for the calcium pump of the sarcoplasmic reticulum ...

Cardiovascular Research, Original Article, Wolfgang F. Bluhm, Markus Meyer, M.Richard Sayen, Eric A. Swanson, Wolfgang H. Dillmann

Date : 01/08/1999
Ehjcardiovascrec

Pharmacological inhibition of CaMKII-but not of protein kinase A-mediated PLB phosphorylation totally abolished the increased effects of β-adrenergic stimulation on cardiac contractility and ...

Cardiovascular Research, Original Article in Review Focus Series on Calmodulin and Ca, Sevdalina Yurukova, Ana Kilić, Katharina Völker, Kirsten Leineweber, Nataliya Dybkova, Lars S. Maier, ...

Date : 01/03/2007
Ehjcardiovascrec

The human receptor was selected for two reasons: (i) compared to other species, human cardiac muscle exhibits the strongest negative inotropic effect induced by β3-AR agonists [5] and, (ii) ...

Cardiovascular Research, Editorial, Enn K. Seppet

Date : 01/08/2003
Ehjcardiovascrec

KeywordsCalcium (cellular)Genetic codeHeart failureSR (function)Ventricular function 1 Introduction The mammalian organism responds to chronic pressure and volume overload of the heart with a ...

Cardiovascular Research, Update review, U Ravens, D Dobrev

Date : 01/01/2000
Ehjcardiovascrec

The encouraging results achieved so far in the field of heart hypertrophy and failure with the aid of engineered mouse models have even suggested consideration for the cardiovascular system as a ...

Cardiovascular Research, Editorial, Carlo Ventura, Gianfranco Pintus, Margherita Maioli

Date : 01/08/1999