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Here, we review the current knowledge about the molecular pathophysiology of CPVT and we discuss some potentially innovative strategies for controlling calcium-handling abnormalities in CPVT that may ...

Cardiovascular Research, Review, Nian Liu, Silvia G. Priori

Date : 15/01/2008 Item size : 341044 bytes

Norepinephrine released by the sympathetic nerves in the heart and epinephrine released into the circulation by adrenal glands increase myocardial contractility by acting on both α- and ...

Cardiovascular Research, Review, Jean-Luc Balligand

Date : 15/08/1999 Item size : 527441 bytes

Ca efflux from the s.r. in one such unit is seen as a spark and the properties of these sparks produce controlled Ca release from the s.r. A major factor controlling the amount of Ca released from ...

Cardiovascular Research, Review, D.A Eisner, A.W Trafford, M.E Dñaz, C.L Overend, S.C O'Neill

Date : 01/06/1998 Item size : 591978 bytes

Abstract Background: Abnormalities of intracellular calcium handling are widely recognized as a common hallmark of heart failure in animal models and humans. Modifying the interaction of ...

Cardiovascular Research, Original Article, Thomas Dieterle, Markus Meyer, Yusu Gu, Darrell D. Belke, Eric Swanson, Mitsuo Iwatate, John Hollander, Kirk L. Peterson, John Ross, Wolfgang H. Dillmann

Date : 01/09/2005

Abstract Objective: We examined the functional consequences of expressing adult rabbit fast skeletal sarcoplasmic reticulum (SR) Ca2+-ATPase (SERCA1a) in isolated adult rat ventricular ...

Cardiovascular Research, Original Article, Nathalie Chossat, Frank Griscelli, Philippe Jourdon, Damien Logeart, Thierry Ragot, Michèle Heimburger, Michel Perricaudet, Anne-Marie Lompré, ...

Date : 01/02/2001

Abstract Objective: The activity of sarcoplasmic reticulum Ca2+-ATPase (SERCA) is reduced in the failing myocardium. [...]transfer of SERCA2a cDNA is considered as a therapeutical ...

Cardiovascular Research, Original Article, Oliver J. Müller, Mathias Lange, Henning Rattunde, Hans-Peter Lorenzen, Matthias Müller, Norbert Frey, Cordula Bittner, Warner Simonides, Hugo A. ...

Date : 01/08/2003

KeywordsCalcium (cellular)IschemiaReperfusionVentricular function 1 Introduction The pivotal role of calcium cycling and homeostasis has long been recognized in contractile, metabolic, electrical and ...

Cardiovascular Research, Update review, J.W.T Fiolet, A Baartscheer

Date : 01/01/2000

Time for primary review 27 days 1 Introduction Heart failure is a syndrome in which dysfunction of the heart causes a mismatch between blood supply and demand of the organs. The pump failure can ...

Cardiovascular Research, Original Article, C Mittmann, T Eschenhagen, H Scholz

Date : 01/08/1998

Methods: Sarcoplasmic reticulum calcium contents were measured immediately prior to drive train-induced aftercontractions in isolated guinea pig cardiac myocytes, using caffeine application under ...

Cardiovascular Research, Original Article, Robin M. Egdell, Ayesha I. De Souza, Kenneth T. Macleod

Date : 01/09/2000

Pulmonary arterial smooth muscle cells (PASMCs) respond to stretch by a calcium increase, a mechanism enhanced during pulmonary hypertension (PH). Methods and results Studies were performed in ...

Cardiovascular Research, Gilbert, Guillaume, Ducret, Thomas, Marthan, Roger, Savineau, Jean-Pierre, Quignard, Jean-François

Date : 15/07/2014