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Ehjcardiovascrec

[...]deregulated calpain activity has been associated with a variety of pathophysiological conditions which have in common the loss of intracellular Ca2+ control.1 A large amount of experimental data ...

Cardiovascular Research, REVIEWS: FOCUS ON THE CALPAIN FAMILY IN THE CARDIOVASCULAR SYSTEM, Javier Inserte, Victor Hernando, David Garcia-Dorado

Date : 01/10/2012 Item size : 559929 bytes
Ehjcardiovascrec

The apparent affinity of CaM for RyR2 was considerably lower in failing sarcoplasmic reticulum (SR) compared with normal SR. [...]the amount of CaM bound to RyR2 was markedly decreased in failing ...

Cardiovascular Research, Original Article, Akihiro Hino, Masafumi Yano, Takayoshi Kato, Masakazu Fukuda, Takeshi Suetomi, Makoto Ono, Wakako Murakami, Takehisa Susa, Shinichi Okuda, Masahiro Doi, ...

Date : 01/12/2012
Ehjcardiovascrec

Chronic hypoxia is a risk factor for COPD patients associated with an increased risk of death,1 and not only right, but also left ventricular (LV) diastolic dysfunction.2 However, little information ...

Cardiovascular Research, Original Article, Karl-Otto Larsen, Birgitte Lygren, Ivar Sjaastad, Kurt A. Krobert, Kristin Arnkværn, Geir Florholmen, Ann-Kristin Ruud Larsen, Finn Olav Levy, Kjetil ...

Date : 01/10/2008
Ehjcardiovascrec

Abstract Objective Experimental and clinical studies have shown that administration of insulin during reperfusion is cardioprotective, but the underlying mechanisms are still unknown. Introduction ...

Cardiovascular Research, Original Article, Yaser Abdallah, Anna Gkatzoflia, Dragan Gligorievski, Sascha Kasseckert, Gerhild Euler, Klaus-Dieter Schlüter, Matthias Schäfer, Hans-Michael Piper, ...

Date : 01/05/2006
Ehjcardiovascrec

Abstract Aims African trypanosomiasis, caused by Trypanosoma brucei species, leads to both neurological and cardiac dysfunction and can be fatal if untreated. The current study exposed isolated ...

Cardiovascular Research, Elliott, Elspeth B., McCarroll, Douglas, Hasumi, Hisashi, Welsh, Claire E., Panissidi, Amanda A., Jones, Nathaniel G., Rossor, Charlotte L., Tait, Andy, Smith, Godfrey L., ...

Date : 01/11/2013 Item size : 279383 bytes
Ehjcardiovascrec

When activated by binding of Ca2+CaM, CaMKII subunits can autophosphorylate neighbouring subunits at Threonine-287 (Thr287) within the CaMKII holoenzyme.2 Autophosphorylation at Thr287 results in ...

Cardiovascular Research, Joiner, Mei-ling Anne

Date : 01/12/2013 Item size : 127391 bytes
Ehjcardiovascrec

Methods and results We performed optical Ca2+ and membrane potential imaging in ventricular myocytes and intact cardiac muscles as well as surface ECGs on a CPVT mouse model with a mutation in ...

Cardiovascular Research, Radwański, Przemysław B., Brunello, Lucia, Veeraraghavan, Rengasayee, Ho, Hsiang-Ting, Lou, Qing, Makara, Michael A., Belevych, Andriy E., Anghelescu, Mircea, Priori, ...

Date : 01/04/2015
Ehjcardiovascrec

Unzipping the N-terminal from the central domain leads to RyR2 hyperactivation and Ca2+ leak from the SR, ultimately causing heart failure.3 Mutations in the three domains of RyR2 were reported to ...

Cardiovascular Research, Pucéat, Michel

Date : 01/09/2010
Ehjcardiovascrec

The apparent affinity of CaM for RyR2 was considerably lower in failing sarcoplasmic reticulum (SR) compared with normal SR. [...]the amount of CaM bound to RyR2 was markedly decreased in failing ...

Cardiovascular Research, Hino, Akihiro, Yano, Masafumi, Kato, Takayoshi, Fukuda, Masakazu, Suetomi, Takeshi, Ono, Makoto, Murakami, Wakako, Susa, Takehisa, Okuda, Shinichi, Doi, Masahiro, Kobayashi, ...

Date : 01/12/2012 Item size : 292305 bytes
Ehjcardiovascrec

Chronic hypoxia is a risk factor for COPD patients associated with an increased risk of death,1 and not only right, but also left ventricular (LV) diastolic dysfunction.2 However, little information ...

Cardiovascular Research, Larsen, Karl-Otto, Lygren, Birgitte, Sjaastad, Ivar, Krobert, Kurt A., Arnkværn, Kristin, Florholmen, Geir, Larsen, Ann-Kristin Ruud, Levy, Finn Olav, Taskén, Kjetil, ...

Date : 01/10/2008