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Methods: Rat mesenteric small arteries (RMSA) were mounted on a pressure myograph and the functional (lumen diameter and Ca2+ oscillations) and ultrastructural effects of the phosphatase inhibitor ...

Cardiovascular Research, Original Article in Review Focus Series on Caveolae in Cardiovascular Signaling, Linda Shaw, Michele A. Sweeney, Stephen C. O'Neill, Carolyn J.P. Jones, Clare Austin, Michael ...

Date : 01/03/2006 Item size : 281926 bytes

The purpose of the present study was to determine whether gender influences the acute electrophysiological actions of genistein at the level of isolated cardiac myocytes and to elucidate the ...

Cardiovascular Research, Original Article, Reginald Liew, Mark A Stagg, Joachim Chan, Peter Collins, Kenneth T MacLeod

Date : 01/01/2004 Item size : 280335 bytes

Ca efflux from the s.r. in one such unit is seen as a spark and the properties of these sparks produce controlled Ca release from the s.r. A major factor controlling the amount of Ca released from ...

Cardiovascular Research, Review, D.A Eisner, A.W Trafford, M.E Dñaz, C.L Overend, S.C O'Neill

Date : 01/06/1998 Item size : 591978 bytes

Abstract Objective: The aim was to determine whether myofilament Ca2+ sensitivity is altered in skinned cardiac fibres from endotoxin-treated rabbits. Methods: Endotoxin was injected i.v. in ...

Cardiovascular Research, Original Article, Benoı̂t Tavernier, Delphine Garrigue, Claire Boulle, Benoı̂t Vallet, Pascal Adnet

Date : 01/05/1998

In turn, mitochondrial fusion is mediated by two mitofusins (MFN1 and MFN2),2 which are involved in outer membrane fusion, and OPA1 (optic atrophic type 1 protein), which is closely linked to the ...

Cardiovascular Research, Original Article, Jerome Piquereau, Fanny Caffin, Marta Novotova, Alexandre Prola, Anne Garnier, Philippe Mateo, Dominique Fortin, Le Ha Huynh, Valérie Nicolas, Marcel V. ...

Date : 01/06/2012

Abstract Objectives: Characterization of an in vitro model of endothelin-1 induced hypertrophy of cultured neonatal rat ventricular myocytes and subsequent analysis of transcription regulation of the ...

Cardiovascular Research, Original Article, Han A.A. van Heugten, Marga C. van Setten, Karin Eizema, Pieter D. Verdouw, Jos M.J. Lamers

Date : 01/02/1998

[...]we investigated the effect of trapidil on the phosphorylation state of phospholamban (PLB), a major PKA target in the heart and key regulator of Ca2+ sequestration via the sarcoplasmic reticulum ...

Cardiovascular Research, Original Article, Oliver J Sichelschmidt, Claudia Hahnefeld, Thomas Hohlfeld, Friedrich W Herberg, Karsten Schrör

Date : 01/06/2003

Abstract Aims We have previously described in rat basilar arterial myocytes that in the absence of extracellular Ca2+ influx, activation of L-type Ca2+ channels stimulates a metabotropic cascade ...

Cardiovascular Research, Original Article, Eva Calderón-Sánchez, Miguel Fernández-Tenorio, Antonio Ordóñez, José López-Barneo, Juan Ureña

Date : 01/04/2009

Abstract Objective: We examined the functional consequences of expressing adult rabbit fast skeletal sarcoplasmic reticulum (SR) Ca2+-ATPase (SERCA1a) in isolated adult rat ventricular ...

Cardiovascular Research, Original Article, Nathalie Chossat, Frank Griscelli, Philippe Jourdon, Damien Logeart, Thierry Ragot, Michèle Heimburger, Michel Perricaudet, Anne-Marie Lompré, ...

Date : 01/02/2001

Abstract Objective: This study examines the relative ability of sodium current (INa)-stimulated reverse mode Na/Ca exchange and the L-type calcium current (ICa) to trigger calcium-induced calcium ...

Cardiovascular Research, Original Article, A.M Evans, M.B Cannell

Date : 01/08/1997