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Heart

Objective To clarify the clinical characteristics and epidemiology of idiopathic pulmonary arterial hypertension (IPAH) in childhood, a rare condition with a bad prognosis, poorly documented in ...

Heart, Pulmonary hypertension, S Moledina, A A Hislop, H Foster, I Schulze-Neick, S G Haworth

Date : 01/09/2010
Heart

OBJECTIVE--To investigate the effect of intracardiac repair on the abnormal biosynthesis of prostacyclin (PGI2) and thromboxane A2 (TXA2) in children with congenital heart disease and increased ...

British Heart Journal, Research Article, I Adatia, S E Barrow, P D Stratton, J M Ritter, S G Haworth

Date : 01/11/1994
Heart

OBJECTIVE--To evaluate whether circulating endothelin, a peptide that is thought to play a part in mediating vascular tone, might be high in pulmonary hypertensive congenital heart ...

British Heart Journal, Research Article, I Adatia, S G Haworth

Date : 01/03/1993
Heart

BACKGROUND--Children with cyanotic congenital heart disease and pulmonary outflow tract obstruction have shortened platelet survival times and are susceptible to thrombosis and organ ...

British Heart Journal, Research Article, I Adatia, S E Barrow, P Stratton, J M Ritter, S G Haworth

Date : 01/02/1993
Heart

Nerves containing peptides that supply the human intrapulmonary vasculature were studied in 21 controls aged one month to 24 years and in 13 patients with pulmonary hypertension aged 11 days to eight ...

British Heart Journal, Research Article, K M Allen, J Wharton, J M Polak, S G Haworth

Date : 01/11/1989
Heart

Pulmonary vascular resistance was measured in air, oxygen, and after administration of vasodilators in 14 children with pulmonary hypertension and congenital heart disease. In this selected group of ...

British Heart Journal, Research Article, A Bush, C M Busst, S G Haworth, A A Hislop, W B Knight, B Corrin, E A Shinebourne

Date : 01/04/1988
Heart

The findings did not suggest a period of normality after birth when the pulmonary artery might have been banded most effectively. Six patients with medial hypertrophy had some reduction in pulmonary ...

British Heart Journal, Research Article, E Juaneda, S G Haworth

Date : 01/05/1985
Heart

The clinical features of eight patients with tetralogy of Fallot and major aortopulmonary collateral arteries were determined and found to be usually unhelpful in differentiating such patients from ...

British Heart Journal, Research Article, J M Ramsay, F J Macartney, S G Haworth

Date : 01/02/1985
Heart

Of the four patients with an increased pulmonary blood flow immediately before operation, there was a significant increase in pulmonary vascular smooth muscle despite three of the patients having had ...

British Heart Journal, Research Article, E Juaneda, S G Haworth

Date : 01/11/1984
Heart

Pulmonary vascular structure was studied by analysing serial reconstructions of the arterial pathways and random sections of tissue in the lungs of 16 children who died with different types of ...

British Heart Journal, Research Article, S G Haworth

Date : 01/11/1984