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Citation Michael Böhm, Rita Kirchmayr, Erland Erdmann; Myocardial Giα-protein levels in patients with hypertensive cardiac hypertrophy, ischemic heart disease and cardiogenic shock, ...

Cardiovascular Research, Böhm, Michael, Kirchmayr, Rita, Erdmann, Erland

Date : 01/10/1995

Abstract Abnormal intracellular Ca2+-handling appears to be a major cause of systolic and diastolic dysfunction in animals and humans with cardiac hypertrophy due to pressure overload and heart ...

Cardiovascular Research, Zolk, Oliver, Flesch, Markus, Nickenig, Georg, Schnabel, Petra, Böhm, Michael

Date : 01/07/1998 Item size : 667449 bytes

Introduction Hypercholesterolaemia is a major risk factor for cardiovascular diseases.1 An important strategy in the reduction of cardiovascular risk includes a healthy diet and lifestyle.2 ...

Cardiovascular Research, Weingärtner, Oliver, Ulrich, Christof, Lütjohann, Dieter, Ismail, Kenan, Schirmer, Stephan H., Vanmierlo, Tim, Böhm, Michael, Laufs, Ulrich

Date : 01/06/2011 Item size : 282450 bytes

Methods and results Ten-week-old male C57/Bl6 wild-type (WT) and eNOS mice (eNOS were subjected to transverse aortic constriction (TAC, 360 μm, 35 days) or sham operation inducing cardiac ...

Cardiovascular Research, Kazakov, Andrey, Müller, Patrick, Jagoda, Philippe, Semenov, Alexander, Böhm, Michael, Laufs, Ulrich

Date : 01/03/2012 Item size : 274600 bytes

In addition to cholesterol-lowering, statins inhibit the isoprenylation of small G proteins. [...]it was tested if these drugs inhibit Rac1 and RhoA activity in cardiomyocytes and, thereby, prevent ...

Cardiovascular Research, Laufs, Ulrich, Kilter, Heiko, Konkol, Christian, Wassmann, Sven, Böhm, Michael, Nickenig, Georg

Date : 01/03/2002 Item size : 280897 bytes

In addition to their lipid-lowering effects, one central biological action of statins is their ability to ameliorate the impaired bioavailability of NO.1 Mechanistically, this occurs through ...

Cardiovascular Research, Schirmer, Stephan H., Werner, Christian M., Laufs, Ulrich, Böhm, Michael

Date : 01/06/2012 Item size : 149958 bytes

In patients undergoing cardiac surgery, the prevalence of AF was associated with increased atrial Rac1 expression.3 Furthermore, the majority of old mice (16 months) with heart-specific ...

Cardiovascular Research, Reil, Jan-Christian, Hohl, Mathias, Oberhofer, Martin, Kazakov, Andrey, Kaestner, Lars, Mueller, Patrick, Adam, Oliver, Maack, Christoph, Lipp, Peter, Mewis, Christian, ...

Date : 01/08/2010 Item size : 289801 bytes

Abstract Objective: Treatment with the β-blocker carvedilol leads to an improvement of outcome and ejection fraction in heart failure. Results: β-Adrenoceptors were downregulated and ...

Cardiovascular Research, Böhm, Michael, Ettelbrück, Sylvia, Flesch, Markus, van Gilst, Wiek H, Knorr, Andreas, Maack, Christoph, Pinto, Yigal M, Paul, Martin, Teisman, Ard C.H, Zolk, Oliver

Date : 01/10/1998

The number of fibrocytes (CD45pos collagen Ipos cells) in the peripheral blood and in the bone marrow was increased both by TAC and l-NAME. l-NAME but not the inhibitor of inducible NOS 1400 W and of ...

Cardiovascular Research, Kazakov, Andrey, Hall, Rabea, Jagoda, Philippe, Bachelier, Katrin, Müller-Best, Patrick, Semenov, Alexander, Lammert, Frank, Böhm, Michael, Laufs, Ulrich

Date : 01/11/2013 Item size : 303800 bytes

Methods and results Pressure overload induced by transaortic constriction (TAC, C57/Bl6 mice, 360 µm for 35 days) increased left ventricular (LV) systolic pressure, the ratio of heart weight to ...

Cardiovascular Research, Müller, Patrick, Kazakov, Andrey, Semenov, Alexander, Böhm, Michael, Laufs, Ulrich

Date : 01/01/2008