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Ehjcardiovascrec

In addition to cholesterol-lowering, statins inhibit the isoprenylation of small G proteins. [...]it was tested if these drugs inhibit Rac1 and RhoA activity in cardiomyocytes and, thereby, prevent ...

Cardiovascular Research, Laufs, Ulrich, Kilter, Heiko, Konkol, Christian, Wassmann, Sven, Böhm, Michael, Nickenig, Georg

Date : 01/03/2002
Ehjcardiovascrec

Abstract Objective: To characterize the cardiac angiotensin and endothelin (ET) system in compensated left ventricular hypertrophy due to long standing arterial hypertension and to assess the role of ...

Cardiovascular Research, Zolk, Oliver, Quattek, Jessika, Seeland, Ute, El-Armouche, Ali, Eschenhagen, Thomas, Böhm, Michael

Date : 01/02/2002
Ehjcardiovascrec

Abstract Worldwide, the numbers of women who have a pre-existing cardiovascular disease or develop cardiac problems during pregnancy are increasing and, due to the lack of evidenced-based data, this ...

Cardiovascular Research, Sliwa, Karen, Böhm, Michael

Date : 15/03/2014 Item size : 250631 bytes
Ehjcardiovascrec

Abstract Abnormal intracellular Ca2+-handling appears to be a major cause of systolic and diastolic dysfunction in animals and humans with cardiac hypertrophy due to pressure overload and heart ...

Cardiovascular Research, Zolk, Oliver, Flesch, Markus, Nickenig, Georg, Schnabel, Petra, Böhm, Michael

Date : 01/07/1998 Item size : 611640 bytes
Ehjcardiovascrec

Abstract Objective: Treatment with the β-blocker carvedilol leads to an improvement of outcome and ejection fraction in heart failure. Results: β-Adrenoceptors were downregulated and ...

Cardiovascular Research, Böhm, Michael, Ettelbrück, Sylvia, Flesch, Markus, van Gilst, Wiek H, Knorr, Andreas, Maack, Christoph, Pinto, Yigal M, Paul, Martin, Teisman, Ard C.H, Zolk, Oliver

Date : 01/10/1998 Item size : 294534 bytes
Ehjournal

The Supplemental Benefit of an Angiotensin Receptor Blocker in Hypertensive Patients with Stable Heart Failure Using Olmesartan (SUPPORT, NCT00417222) trial, a prospective, randomized, open-label ...

European Heart Journal, Ewen, Sebastian, Böhm, Michael

Date : 14/04/2015 Item size : 203453 bytes
Ehjournal

A new Transregional Collaborative Research Center of the German Research Foundation (DFG) has been created to address reno-cardiovascular interactions underlying the increased cardiovascular risk in ...

European Heart Journal, Noels, Heidi, Boor, Peter, Goettsch, Claudia, Hohl, Mathias, Jahnen-Dechent, Wilhelm, Jankowski, Vera, Kindermann, Ingrid, Kramann, Rafael, Lehrke, Michael, Linz, Dominik, ...

Date : 21/03/2018 Item size : 164700 bytes
Ehjournal

Systolic blood pressure, cardiovascular outcomes and efficacy and safety of sacubitril/valsartan (LCZ696) in patients with chronic heart failure and reduced ejection fraction: results from ...

European Heart Journal, Böhm, Michael, Young, Robin, Jhund, Pardeep S., Solomon, Scott D., Gong, Jianjian, Lefkowitz, Martin P., Rizkala, Adel R., Rouleau, Jean L., Shi, Victor C., Swedberg, Karl, ...

Date : 14/04/2017 Item size : 377845 bytes
Ehjournal

Abstract Aims Although active-controlled trials with reninangiotensin inhibitors are ethically mandated in heart failure with reduced ejection fraction, clinicians and regulators often want to know ...

European Heart Journal, McMurray, John, Packer, Milton, Desai, Akshay, Gong, Jianjian, Greenlaw, Nicola, Lefkowitz, Martin, Rizkala, Adel, Shi, Victor, Rouleau, Jean, Solomon, Scott, Swedberg, Karl, ...

Date : 14/02/2015 Item size : 312688 bytes
Ehjournal

Methods and results In this multicentre trial, 63 PPCM patients with left ventricular ejection fraction (LVEF) 35% were randomly assigned to short-term (1W: bromocriptine, 2.5mg, 7 days) or long-term ...

European Heart Journal, Hilfiker-Kleiner, Denise, Haghikia, Arash, Berliner, Dominik, Vogel-Claussen, Jens, Schwab, Johannes, Franke, Annegret, Schwarzkopf, Marziel, Ehlermann, Philipp, Pfister, ...

Date : 14/09/2017 Item size : 376775 bytes