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Ehjournal

Introduction Hypertrophic cardiomyopathy (HCM) is a heterogeneous genetic disease characterized by the development of left ventricular hypertrophy (LVH) in the absence of abnormal loading conditions ...

European Heart Journal, Monserrat, Lorenzo, López, Begoña, González, Arantxa, Hermida, Manuel, Fernández, Xusto, Ortiz, Martín, Barriales-Villa, Roberto, Castro-Beiras, Alfonso, ...

Date : 01/01/2011 Item size : 282084 bytes
Ehjournal

Introduction Cardiomyocyte apoptosis has been shown to be abnormally stimulated in hypertensive heart disease (HHD), defined by the presence of left ventricular hypertrophy (LVH) in the absence of ...

European Heart Journal, Ravassa, Susana, González, Arantxa, López, Begoña, Beaumont, Javier, Querejeta, Ramón, Larman, Mariano, Díez, Javier

Date : 01/11/2007
Ehjcardiovascrec

[...]although hypertension increases the risk for developing HF,1 LVH itself is an independent risk factor for HF.1,2 Furthermore, in spite of the continuous progress of antihypertensive strategies ...

Cardiovascular Research, González, Arantxa, López, Begoña, Ravassa, Susana, Beaumont, Javier, Arias, Teresa, Hermida, Nerea, Zudaire, Amaia, Díez, Javier

Date : 15/02/2009
Ehjcardiovascrec

Abstract Aim We investigated whether P144, a synthetic peptide from transforming growth factor-β1 (TGF-β1) type III receptor betaglycan, exhibits cardiac antifibrotic properties. Compared with ...

Cardiovascular Research, Hermida, Nerea, López, Begoña, González, Arantxa, Dotor, Javier, Lasarte, Juan José, Sarobe, Pablo, Borrás-Cuesta, Francisco, Díez, Javier

Date : 15/02/2009 Item size : 300403 bytes
Ehjcardiovascrec

Introduction Myocardial fibrosis may contribute to the development and progression of chronic heart failure (HF) in patients with hypertensive heart disease (HHD).1 A linkage between fibrosis and ...

Cardiovascular Research, López, Begoña, González, Arantxa, Lindner, Diana, Westermann, Dirk, Ravassa, Susana, Beaumont, Javier, Gallego, Idoia, Zudaire, Amaia, Brugnolaro, Cristina, ...

Date : 01/07/2013 Item size : 336777 bytes
Ehjcardiovascrec

Abstract Aim To address the mechanisms responsible for the increase in LV filling pressures induced by acute hypertension transients in patients with heart failure with preserved ejection fraction ...

Cardiovascular Research, Pérez del Villar, Candelas, Savvatis, Konstantinos, López, Begoña, Kasner, Mario, Martinez-Legazpi, Pablo, Yotti, Raquel, González, Arantxa, Díez, Javier, ...

Date : 01/07/2017
Ehjcardiovascrec

Altered cardiac expression of peroxisome proliferator-activated receptor-isoforms in patients with hypertensive heart disease Abstract Objective: To investigate whether cardiac expression of the ...

Cardiovascular Research, Goikoetxea, María J., Beaumont, Javier, González, Arantxa, López, Begoña, Querejeta, Ramón, Larman, Mariano, Díez, Javier

Date : 01/03/2006
Ehjcardiovascrec

According to the classical view, necrosis is the major mechanism of cardiomyocyte death in cardiac diseases. [...]the perspectives of strategies aimed to detect and modulate apoptosis of ...

Cardiovascular Research, González, Arantxa, Fortuño, Marı́a A, Querejeta, Ramón, Ravassa, Susana, López, Begoña, López, Natalia, Dı́ez, Javier

Date : 01/09/2003 Item size : 598617 bytes
Ehjournal

Whereas autopsy descriptions of MF can provide a global view, in invivo studies, sampling is limited by biopsy size, and fibrosis is typically described only by the quantity of collagen deposition ...

European Heart Journal, Treibel, Thomas A., López, Begoña, González, Arantxa, Menacho, Katia, Schofield, Rebecca S., Ravassa, Susana, Fontana, Marianna, White, Steven K., DiSalvo, Carmelo, ...

Date : 14/11/2017
Ehjournal

Whereas autopsy descriptions of MF can provide a global view, in invivo studies, sampling is limited by biopsy size, and fibrosis is typically described only by the quantity of collagen deposition ...

European Heart Journal, Treibel, Thomas A., López, Begoña, González, Arantxa, Menacho, Katia, Schofield, Rebecca S., Ravassa, Susana, Fontana, Marianna, White, Steven K., DiSalvo, Carmelo, ...

Date : 15/11/2017