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Ehjournal

The causality of plasma low-density lipoprotein-cholesterol (LDL-C) and reduced LDL receptor-mediated LDL uptake in the pathophysiology of ASCVD has been established beyond any reasonable doubt.3 For ...

European Heart Journal, Landmesser, Ulf, John Chapman, M., Farnier, Michel, Gencer, Baris, Gielen, Stephan, Hovingh, G. Kees, Lüscher, Thomas F., Sinning, David, Tokgözoğlu, Lale, Wiklund, ...

Date : 08/03/2017 Item size : 424498 bytes
Ehjournal

The causality of plasma low-density lipoprotein-cholesterol (LDL-C) and reduced LDL receptor-mediated LDL uptake in the pathophysiology of ASCVD has been established beyond any reasonable doubt.3 For ...

European Heart Journal, Landmesser, Ulf, John Chapman, M., Farnier, Michel, Gencer, Baris, Gielen, Stephan, Hovingh, G. Kees, Lüscher, Thomas F., Sinning, David, Tokgözoğlu, Lale, Wiklund, ...

Date : 09/03/2017
Ehjournal

Abstract Aims The deacetylase sirtuin 1 (Sirt1) exerts beneficial effects on lipid metabolism, but its roles in plasma LDL-cholesterol regulation and atherosclerosis are controversial. [...]we ...

European Heart Journal, Miranda, Melroy X., van Tits, Lambertus J., Lohmann, Christine, Arsiwala, Tasneem, Winnik, Stephan, Tailleux, Anne, Stein, Sokrates, Gomes, Ana P., Suri, Vipin, Ellis, James ...

Date : 01/01/2015
Ehjournal

Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors are a new class of drugs able to decrease LDL-C by 5070% when administered either as a monotherapy or on a background with statins.46 ...

European Heart Journal, Lüscher, Thomas F.

Date : 21/09/2015
Ehjournal

Furthermore, the EMPA-REG OUTCOME trial using the novel antihyperglycaemic agent, empagliflozin,8 a selective sodiumglucose co- transporter inhibitor, significantly reduced cardiovascular mortality; ...

European Heart Journal, Lüscher, Thomas F.

Date : 07/02/2016 Item size : 183395 bytes
Ehjournal

The Framingham study and numerous cohorts thereafter subsequently confirmed the prognostic value of cholesterol and in particular LDL-cholesterol, and the 4S Trial 2 eventually proved the cholesterol ...

European Heart Journal, Lüscher, Thomas F.

Date : 14/10/2016 Item size : 195035 bytes
Ehjournal

Download the Issue @ a Glance podcast Subscribe to the EHJ Podcast Elevated levels of LDL-cholesterol are determined mainly genetically1 and are the most important risk factor for atherosclerosis in ...

European Heart Journal, Lüscher, Thomas F.

Date : 01/05/2016 Item size : 186101 bytes
Ehjournal

Citation Ulf Landmesser, M. John Chapman, Michel Farnier, Baris Gencer, Stephan Gielen, G. Kees Hovingh, Thomas F. Lüscher, David Sinning, Lale Tokgözo lu, Olov Wiklund, Jose Luis Zamorano, ...

European Heart Journal, Landmesser, Ulf, John Chapman, M., Farnier, Michel, Gencer, Baris, Gielen, Stephan, Hovingh, G. Kees, Lüscher, Thomas F., Sinning, David, Tokgözoğlu, Lale, Wiklund, ...

Date : 01/08/2017
Ehjournal

Prevention has experienced enormous progress over the last decades with the development of effective antihypertensive drugs and then aspirin and statins1 as outlined in the most recent ESC ...

European Heart Journal, Lüscher, Thomas F.

Date : 01/08/2017
Ehjournal

Prevention has experienced enormous progress over the last decades with the development of effective antihypertensive drugs and then aspirin and statins1 as outlined in the most recent ESC ...

European Heart Journal, Lüscher, Thomas F.

Date : 01/08/2017 Item size : 114014 bytes