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[...]window of preconditioning normalizes palmitate use for oxidation and improves function during low-flow ischaemia Conclusion Thus, the second window of preconditioning normalized oxidative ...

Cardiovascular Research, Original Article, Raymond K. Kudej, Mathew Fasano, Xin Zhao, Gary D. Lopaschuk, Susan K. Fischer, Dorothy E. Vatner, Stephen F. Vatner, E. Douglas Lewandowski

Date : 01/12/2011 Item size : 326863 bytes

[...]a decrease in ATP production in cardiomyocytes will cause a decrease in Ca2+ gradients across the sarcolemmal and sarcoplasmic membranes, together with elevated cytoplasmic Ca2+ levels, as is ...

Cardiovascular Research, Review, Desiree Abdurrachim, Joost J.F.P. Luiken, Klaas Nicolay, Jan F.C. Glatz, Jeanine J. Prompers, Miranda Nabben

Date : 01/05/2015 Item size : 553034 bytes

Several studies, including investigations in humans, have clearly shown an important pathophysiological role of this pathway in the cardiovascular system and in disease states such as hypertension, ...

Cardiovascular Research, Editorial, Stephan L.M. Peters, Martin C. Michel

Date : 01/07/2007 Item size : 162404 bytes

KeywordsCardiomyopathyHeart failureContractile functionRemodelingVentricular functionTime for primary review 33 days. 1 Introduction Heart failure was defined by Braunwald as the pathophysiologic ...

Cardiovascular Research, Review, Stefan Hein, Sawa Kostin, Annette Heling, Yoshi Maeno, Jutta Schaper

Date : 14/01/2000 Item size : 261696 bytes

Understanding the signaling mechanisms of these receptors in the context of the heart is likely to provide a better therapeutic approach towards treatment of heart failure. Introduction Activation ...

Cardiovascular Research, Review, Liza Barki-Harrington, Cinzia Perrino, Howard A Rockman

Date : 15/08/2004 Item size : 572672 bytes

In this review, we discuss the measurement principles of all invasive and non-invasive techniques that are used to assess the local effects of cardiac regenerative therapy in order to improve ...

European Heart Journal - Cardiovascular Imaging, REVIEW PAPER, Frebus J. van Slochteren, Arco J. Teske, Tycho I.G. van der Spoel, Stefan Koudstaal, Pieter A. Doevendans, Joost P.G. Sluijter, Maarten ...

Date : 01/10/2012

Abstract Decreased amplitude and slower kinetics of cardiomyocyte intracellular calcium (Cai2+) transients may underlie the diminished cardiac function observed in heart failure. Objective: Since ...

Cardiovascular Research, Original Article, Andrzej M Janczewski, Maliha Zahid, Bonnie H Lemster, Carol S Frye, Gregory Gibson, Yoshihiro Higuchi, Evangelia G Kranias, Arthur M Feldman, Charles F ...

Date : 01/06/2004

Abstract Objective: We have previously shown that cardiac-directed expression of adenylycyclase type VI (ACVI) increases heart function in transgenic mice, and improves heart function and survival in ...

Cardiovascular Research, Original Article, Mei Hua Gao, Hamed Bayat, David M Roth, Jin Yao Zhou, Jeffrey Drumm, John Burhan, H Kirk Hammond

Date : 01/11/2002

Abstract Objective The purpose of the present study was to determine whether increased activation of the RhoA/Rho-kinase (ROCK) pathway occurs in diabetic cardiomyopathy and whether acute inhibition ...

Cardiovascular Research, Original Article, Guorong Lin, Graham P. Craig, Lili Zhang, Violet G. Yuen, Michael Allard, John H. McNeill, Kathleen M. MacLeod

Date : 01/07/2007

Pharmacological inhibition of CaMKII-but not of protein kinase A-mediated PLB phosphorylation totally abolished the increased effects of β-adrenergic stimulation on cardiac contractility and ...

Cardiovascular Research, Original Article in Review Focus Series on Calmodulin and Ca, Sevdalina Yurukova, Ana Kilić, Katharina Völker, Kirsten Leineweber, Nataliya Dybkova, Lars S. Maier, ...

Date : 01/03/2007