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Abstract Aims Recent studies from our laboratory demonstrated that increased expression of the small GTP-binding protein RhoA and activation of the RhoA/rho kinase (ROCK) pathway play an important ...

Cardiovascular Research, Original Article, Hesham Soliman, Graham P. Craig, Prabhakar Nagareddy, Violet G. Yuen, Guorong Lin, Ujendra Kumar, John H. McNeill, Kathleen M. MacLeod

Date : 15/07/2008 Item size : 280187 bytes

[...]cell therapy is faced with a number of challenges, including survival of the transplanted cells in the infarct region, which is characterized by abundant levels of oxidants and lack of a ...

Cardiovascular Research, Original Article, Mahmood Khan, Sarath Meduru, Rajan Gogna, Esha Madan, Lucas Citro, Muthulakshmi L. Kuppusamy, Muzzammil Sayyid, Mahmoud Mostafa, Robert L. Hamlin, Periannan ...

Date : 01/01/2012 Item size : 322521 bytes

Isoproterenol‐induced heart failure in the rat is associated with nitric oxide‐dependent functional alterations of cardiac function Tel: +421 2 50117 376, Fax: +421 2 50117 100, Email: ...

European Journal of Heart Failure, Krenek, Peter, Kmecova, Jana, Kucerova, Dana, Bajuszova, Zuzana, Musil, Peter, Gazova, Andrea, Ochodnicky, Peter, Klimas, Jan, Kyselovic, Jan

Date : 01/02/2009 Item size : 178559 bytes

Role of neuronal nitric oxide synthase in lipopolysaccharide-induced tumor necrosis factor-alpha expression in neonatal mouse cardiomyocytes Calcium in turn modulates extracellular signal-related ...

Cardiovascular Research, Original Article, Nicola Geoghegan-Morphet, Dylan Burger, Xiangru Lu, Venkatachalem Sathish, Tianqing Peng, Stephen M. Sims, Qingping Feng

Date : 15/07/2007 Item size : 270277 bytes

KeywordsCholesterolContractile functionLipoproteinsOxygen radicalsTransgenic animal models Time for primary review 20 days 1 Introduction Atherosclerosis results in coronary heart disease (CHD), one ...

Cardiovascular Research, Original Article, Tamás Csont, Erika Bereczki, Péter Bencsik, Gabriella Fodor, Anikó Görbe, Ágnes Zvara, Csaba Csonka, László G. Puskás, Miklós ...

Date : 01/10/2007 Item size : 308363 bytes

Recap on NOS distribution and function in cardiovascular tissues Nitric oxide (NO) is a key universal signalling molecule in the cardiovascular system, acting on both acute and more chronic ...

Cardiovascular Research, REVIEWS: SPOTLIGHT ON REDUCING MYOCARDIAL ISCHAEMIA/REPERFUSION INJURY, Boris Manoury, Virginie Montiel, Jean-Luc Balligand

Date : 01/05/2012 Item size : 553690 bytes

HSPA12B is a member of a newly identified subfamily of the Hsp70 family of heat shock proteins and is predominately expressed in endothelial cells.1,2 Blood pressure may play a role in its ...

Cardiovascular Research, Editorial, Fouad A. Zouein, Mazen Kurdi, George W. Booz

Date : 01/09/2013 Item size : 186051 bytes

Abstract Aim The effects of nitric oxide (NO) in the cardiovascular system are attributed in part to cGMP synthesis by the α1β1 isoform of soluble guanylate cyclase (sGC). Because available ...

Cardiovascular Research, Original Article, Emmanuel S. Buys, Patrick Sips, Pieter Vermeersch, Michael J. Raher, Elke Rogge, Fumito Ichinose, Mieke Dewerchin, Kenneth D. Bloch, Stefan Janssens, Peter ...

Date : 01/07/2008

Results: Contrary to our hypothesis, aging decreased responsiveness of coronary arterioles to endothelin (ET, 1 × 10113 × 108 M), potassium chloride (KCl, 10100 mM), and pressure-induced ...

Cardiovascular Research, Original Article, Robert D. Shipley, Judy M. Muller-Delp

Date : 01/05/2005

Several differences between right and left heart are known: the effect of cardiac contraction on coronary arterial inflow, autoregulation, and oxygen extraction. [1] show in their study the ...

Cardiovascular Research, Editorial, N. Westerhof

Date : 01/12/2004