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There is mounting evidence that thrombin acts as a powerful modulator of many processes like regulation of vascular tone, permeability, migration and proliferation of VSMC, recruitment of monocytes ...

Cardiovascular Research, Review, Julian Ilcheff Borissoff, Henri M.H. Spronk, Sylvia Heeneman, Hugo ten Cate

Date : 01/06/2009 Item size : 584450 bytes

Based on these observations and the biological effects induced by ET-1, including profound vasoconstriction, pro-inflammatory actions, mitogenic and proliferative effects, stimulation of free radical ...

Cardiovascular Research, Review, Felix Böhm, John Pernow

Date : 01/10/2007 Item size : 470334 bytes

Tel: + 41 21 314 60 53, Fax: +41 21 314 61 08, Email: Search for more papers by this author Stott David J., Institute of Cardiovascular and Medical Sciences, University of ...

European Journal of Heart Failure, Nanchen, David, Stott, David J., Gussekloo, Jacobijn, Mooijaart, Simon P., Westendorp, Rudi G.J., Jukema, J. Wouter, Macfarlane, Peter W., Cornuz, Jacques, Rodondi, ...

Date : 01/05/2013 Item size : 178234 bytes

Abstract Aldosterone is well recognized as a cause of sodium reabsorption, water retention, and potassium and magnesium loss; however, it also produces a variety of other actions that lead to ...

Cardiovascular Research, Review, Allan D Struthers, Thomas M MacDonald

Date : 01/03/2004 Item size : 333477 bytes

Abstract Objective: Endothelial dysfunction is an early risk factor for cardiovascular disease and hypertension. Results: In cultured aortic endothelial cells, iptakalim caused a ...

Cardiovascular Research, Original Article, Hai Wang, Chaoliang Long, Zhibian Duan, Cuige Shi, Guodong Jia, Yingli Zhang

Date : 01/02/2007 Item size : 203949 bytes

Conclusion: Cerivastatin, but not gemfibrozil significantly reduces RLP-C increase after an oral fat load in combination with a reversal of fat-load induced endothelial ...

Cardiovascular Research, Original Article, Hanneke W Wilmink, Marcel B Twickler, Jan Dirk Banga, Geesje M Dallinga-Thie, Hans Eeltink, D.Willem Erkelens, Ton J Rabelink, Erik S Stroes

Date : 01/06/2001 Item size : 242418 bytes

Pre-menopausal women have a lower risk of developing hypertension than men or post-menopausal women [1]. [...]animal models such as the spontaneously hypertensive rat (SHR) exhibit sexual dichotomy ...

Cardiovascular Research, Editorial, C. Subah Packer

Date : 01/01/2007 Item size : 156972 bytes

In addition to their lipid-lowering effects, one central biological action of statins is their ability to ameliorate the impaired bioavailability of NO.1 Mechanistically, this occurs through ...

Cardiovascular Research, Editorial, Stephan H. Schirmer, Christian M. Werner, Ulrich Laufs, Michael Böhm

Date : 01/06/2012 Item size : 181712 bytes

The endothelium modulates vascular tone, regulates local cellular growth and the deposition of the extracellular matrix, protects the vessel from the potentially harmful consequences of substances ...

Cardiovascular Research, Review, Kwang Kon Koh

Date : 01/09/2002 Item size : 558962 bytes

Download the Issue @ a Glance podcast Subscribe to the EHJ Podcast In spite of all the progress made over the last decades, atherosclerotic vascular disease remains the most important cause of ...

European Heart Journal, ISSUE @ A GLANCE, Thomas F. Lüscher

Date : 07/06/2016 Item size : 236362 bytes