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[...]the coronary microcirculation is also a target of both injury by myocardial ischaemia/reperfusion and protection from it. The lack of translation is not the consequence of a species problem, ...

Cardiovascular Research, REVIEWS: SPOTLIGHT ON REDUCING MYOCARDIAL ISCHAEMIA/REPERFUSION INJURY, Gerd Heusch, Petra Kleinbongard, Andreas Skyschally, Bodo Levkau, Rainer Schulz, Raimund Erbel

Date : 01/05/2012 Item size : 569039 bytes

The mechanisms of protection by postconditioning include: formation and release of several autacoids and cytokines; maintained acidosis during early reperfusion; activation of protein kinases; ...

Cardiovascular Research, Review, Michel Ovize, Gary F. Baxter, Fabio Di Lisa, Péter Ferdinandy, David Garcia-Dorado, Derek J. Hausenloy, Gerd Heusch, Jakob Vinten-Johansen, Derek M. Yellon, Rainer ...

Date : 01/08/2010

Acute myocardial infarction remains a significant health problem throughout the world, and for those patients surviving the immediate event, infarct size is the main determinant of further ...

Cardiovascular Research, VIEWPOINT EDITORIAL, Gerd Heusch, Rainer Schulz

Date : 01/10/2009 Item size : 328965 bytes

[...]mechanisms independent of the NOS pathway have been suggested to contribute to NO synthesis during ischemia. NO initiates detrimental as well as protective mechanisms in a ...

Cardiovascular Research, Original Article, Claus Martin, Rainer Schulz, Heiner Post, Kerstin Boengler, Malte Kelm, Petra Kleinbongard, Petra Gres, Andreas Skyschally, Ina Konietzka, Gerd Heusch

Date : 01/04/2007 Item size : 303478 bytes

In isolated rat [6,7] and rabbit [8] hearts, SB202190 or SB203580 blocked the ischemia-induced p38 MAP kinase phosphorylation [6] or the ischemia-induced increase in p38 MAP kinase activity [7,8] and ...

Cardiovascular Research, Original Article, Rainer Schulz, Sergej Belosjorow, Petra Gres, Johanna Jansen, Martin C Michel, Gerd Heusch

Date : 15/08/2002

[...]with longer reperfusion ischemic preconditioning diminishes adverse left ventricular remodeling following infarction and improves long-term functional recovery in chronically instrumented ...

Cardiovascular Research, Review, Rainer Schulz, Michael V Cohen, Matthias Behrends, James M Downey, Gerd Heusch

Date : 01/11/2001