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Ehjcardiovascrec

Abstract Aims Elevation of arginase activity has been linked to vascular dysfunction in diabetes and hypertension by a mechanism involving decreased nitric oxide (NO) bioavailability due to ...

Cardiovascular Research, Bhatta, Anil, Yao, Lin, Xu, Zhimin, Toque, Haroldo A., Chen, Jijun, Atawia, Reem T., Fouda, Abdelrahman Y., Bagi, Zsolt, Lucas, Rudolf, Caldwell, Ruth B., Caldwell, Robert W.

Date : 01/11/2017 Item size : 492954 bytes
Ehjcardiovascrec

Introduction In 2016, hypertension was ranked as the leading risk factor for global burden of disease in both developed and underdeveloped countries.1 In the past 10years, it has become evident that ...

Cardiovascular Research, Loperena, Roxana, Van Beusecum, Justin P, Itani, Hana A, Engel, Noah, Laroumanie, Fanny, Xiao, Liang, Elijovich, Fernando, Laffer, Cheryl L, Gnecco, Juan S, Noonan, Jonathan, ...

Date : 01/09/2018 Item size : 521790 bytes
Ehjcardiovascrec

Methods and results Left ventricles (LVs) of intact rat hearts, rabbit papillary muscles and myocardial strips from cardiac surgery patients were stretched. When preload increases, the stretching ...

Cardiovascular Research, Leite-Moreira, André M, Almeida-Coelho, João, Neves, João S, Pires, Ana L, Ferreira-Martins, João, Castro-Ferreira, Ricardo, Ladeiras-Lopes, Ricardo, ...

Date : 01/04/2018 Item size : 365611 bytes
Ehjcardiovascrec

Both platelet and vascular responses to nitric oxide (NO) donors are impaired in HF patients with reduced ejection fraction (HFrEF) compared with healthy volunteers (HVs) due to scavenging of NO, and ...

Cardiovascular Research, Borgognone, Alessandra, Shantsila, Eduard, Worrall, Sophie M, Prompunt, Eakkapote, Loka, Thomas, Loudon, Brodie L, Chimen, Myriam, Ed Rainger, G, Lord, Janet M, Turner, ...

Date : 01/08/2018 Item size : 406241 bytes
Ehjcardiovascrec

Cardiac force adaptations to increased preload are well-known, with a biphasic increase in contractility, i.e. a rapid phase that involves enhanced calcium sensitivity of cardiac myofilaments (the ...

Cardiovascular Research, Balligand, Jean-Luc, Farah, Charlotte

Date : 01/04/2018 Item size : 152449 bytes
Ehjcardiovascrec

Furthermore, loss of BH4 from pro-inflammatory macrophages resulted in increased foam cell formation and altered cellular redox signalling, with decreased expression of antioxidant genes and ...

Cardiovascular Research, Douglas, Gillian, Hale, Ashley B, Patel, Jyoti, Chuaiphichai, Surawee, Al Haj Zen, Ayman, Rashbrook, Victoria S, Trelfa, Lucy, Crabtree, Mark J, McNeill, Eileen, Channon, ...

Date : 01/08/2018 Item size : 429831 bytes
Ehjcardiovascrec

According to the Global Burden of Disease study, cardiovascular risk factors and diseases such as hypertension, ischaemic heart disease, smoking, and cerebrovascular disease are the leading triggers ...

Cardiovascular Research, Münzel, Thomas, Daiber, Andreas

Date : 01/08/2018 Item size : 206245 bytes
Ehjcardiovascrec

In patients who experience an acute myocardial infarction (AMI), a greater extent of myocardial necrosis results in a worse long-term prognosis.1 It is therefore imperative to develop treatments that ...

Cardiovascular Research, Davidson, Sean M, Yellon, Derek M

Date : 01/05/2018 Item size : 160800 bytes
Ehjcardiovascrec

Interestingly, while E2-induced miRNAs predominantly appear to serve protective functions, it could be argued that many X-linked miRNAs have been found to challenge microvascular and myocardial ...

Cardiovascular Research, Florijn, Barend W, Bijkerk, Roel, van der Veer, Eric P, van Zonneveld, Anton Jan

Date : 01/02/2018 Item size : 868278 bytes
Ehjcardiovascrec

Compared to blood leucocytes, which exist as functionally distinct subtypes, platelets are considered to be relatively simple cell fragments that form vascular system plugs without a differentially ...

Cardiovascular Research, Radziwon-Balicka, Aneta, Lesyk, Gabriela, Back, Valentina, Fong, Teresa, Loredo-Calderon, Erica L, Dong, Bin, El-Sikhry, Haitham, El-Sherbeni, Ahmed A, El-Kadi, Ayman, Ogg, ...

Date : 01/12/2017 Item size : 432035 bytes