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In approximately 50% of heart failure patients, systolic function is near normal, while impaired diastolic function restricts filling of the left ventricle with blood.1 This condition is termed heart ...

Cardiovascular Research, Røe, Åsmund T., Aronsen, Jan Magnus, Skårdal, Kristine, Hamdani, Nazha, Linke, Wolfgang A., Danielsen, Håvard E., Sejersted, Ole M., Sjaastad, Ivar, Louch, ...

Date : 01/08/2017 Item size : 386414 bytes

Fibroblast growth factor-2 (FGF-2) plays an instructive role in osteogenesis and bone development, but its role in vascular calcification was unknown. [...]we investigated the involvement of FGF-2 ...

Cardiovascular Research, Borland, Samantha J., Morris, Thomas G., Borland, Shona C., Morgan, Mark R., Francis, Sheila E., Merry, Catherine L.R., Canfield, Ann E.

Date : 01/11/2017 Item size : 371746 bytes

In cultured neonatal rat ventricular cardiomyocytes (NRVM) and NRVM transduced with kinase dead (KD) PKN1 K644R mutant subjected to simulated ischaemia/reperfusion (sI/R), PhosTag® gel analysis ...

Cardiovascular Research, Francois, Asvi A, Obasanjo-Blackshire, Kofo, Clark, James E, Boguslavskyi, Andrii, Holt, Mark R, Parker, Peter J, Marber, Michael S, Heads, Richard J

Date : 01/01/2018 Item size : 478744 bytes

Abstract Aims Tenascin-C (TNC) is an endogenous danger signal molecule strongly associated with inflammatory diseases and with poor outcome in patients with cardiomyopathies. By cross bone marrow ...

Cardiovascular Research, Abbadi, Dounia, Laroumanie, Fanny, Bizou, Mathilde, Pozzo, Joffrey, Daviaud, Danièle, Delage, Christine, Calise, Denis, Gaits-Iacovoni, Fréderique, Dutaur, Marianne, ...

Date : 01/01/2018 Item size : 397692 bytes

Cardiac force adaptations to increased preload are well-known, with a biphasic increase in contractility, i.e. a rapid phase that involves enhanced calcium sensitivity of cardiac myofilaments (the ...

Cardiovascular Research, Balligand, Jean-Luc, Farah, Charlotte

Date : 01/04/2018 Item size : 148205 bytes

In their letter, they react on our recent publication in Cardiovascular Research,1 in which we used four different experimental in vitro and in vivo models to test the acute and chronic effects of ...

Cardiovascular Research, Takanari, Hiroki, Fontes, Magda S C, van der Heyden, Marcel A G, Vos, Marc A, van Veen, Toon A B

Date : 01/12/2017 Item size : 144879 bytes

Myocardial injury is increased in aged hearts during ischaemia-reperfusion (IR) and accelerates the transition to post-infarct heart failure.1 Although many therapeutic interventions can effectively ...

Cardiovascular Research, Chen, Qun, Lesnefsky, Edward J

Date : 01/05/2018 Item size : 144282 bytes