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Abstract Clinical trials have demonstrated morbidity and mortality benefits of mineralocorticoid receptor antagonists (MRAs) in patients with heart failure. Introduction Mineralocorticoid receptor ...

European Journal of Heart Failure, Iqbal, Javaid, Parviz, Yasir, Pitt, Bertram, Newell‐Price, John, Al‐Mohammad, Abdallah, Zannad, Faiez

Date : 01/02/2014 Item size : 223269 bytes

Timing of eplerenone initiation and outcomes in patients with heart failure after acute myocardial infarction complicated by left ventricular systolic dysfunction: insights from the EPHESUS ...

European Journal of Heart Failure, Adamopoulos, Chris, Ahmed, Ali, Fay, Renaud, Angioi, Michael, Filippatos, Gerasimos, Vincent, John, Pitt, Bertram, Zannad, Faiez

Date : 01/11/2009 Item size : 173142 bytes

Serum uric acid is associated with mortality and heart failure hospitalizations in patients with complicated myocardial infarction: findings from the High‐Risk Myocardial Infarction Database ...

European Journal of Heart Failure, von Lueder, Thomas G., Girerd, Nicolas, Atar, Dan, Agewall, Stefan, Lamiral, Zohra, Kanbay, Mehmet, Pitt, Bertram, Dickstein, Kenneth, Zannad, Faiez, Rossignol, ...

Date : 01/11/2015 Item size : 63137 bytes

There has been considerable focus on the risks of hyperkalaemia, especially in patients with chronic kidney disease (CKD), diabetes mellitus, and/or heart failure.13 Although the exact level of serum ...

European Heart Journal, Pitt, Bertram, Rossignol, Patrick

Date : 07/01/2017

Methods and results Of the 2645 systolic HF patients in the Beta-Blocker Evaluation of Survival Trial with data on baseline serum uric acid, 1422 had hyperuricaemia (uric acid 6 mg/dL for women and 8 ...

European Heart Journal, Filippatos, Gerasimos S., Ahmed, Mustafa I., Gladden, James D., Mujib, Marjan, Aban, Inmaculada B., Love, Thomas E., Sanders, Paul W., Pitt, Bertram, Anker, Stefan D., Ahmed, ...

Date : 01/03/2011 Item size : 294630 bytes

Abstract Aims The coronary collateral circulation as an alternative source of blood supply has shown benefits regarding several clinical endpoints in patients with myocardial infarction (MI) such as ...

European Heart Journal, Meier, Pascal, Hemingway, Harry, Lansky, Alexandra J., Knapp, Guido, Pitt, Bertram, Seiler, Christian

Date : 01/03/2012

Improvement in glycaemic control is no longer an acceptable surrogate for efficacy (or safety) with regard to cardiovascular outcomes.35 Safety must be formally demonstrated in adequately powered ...

European Heart Journal, Zannad, Faiez, Stough, Wendy Gattis, Pocock, Stuart J., Sleight, Peter, Cushman, William C, Cleland, John G.F., McMurray, John J.V., Lonn, Eva, Geller, Nancy L., Wedel, Hans, ...

Date : 01/05/2012 Item size : 369253 bytes

Conclusion In a cohort of ambulatory chronic systolic and diastolic HF patients who were balanced in all measured baseline covariates, serum potassium <4 mEq/L was associated with increased ...

European Heart Journal, Ahmed, Ali, Zannad, Faiez, Love, Thomas E., Tallaj, Jose, Gheorghiade, Mihai, Ekundayo, Olaniyi James, Pitt, Bertram

Date : 01/06/2007

Aldosterone blockade, or more correctly mineralocorticoid receptor blockade (MRB), when administered between days 3 and 14 in patients with heart failure (HF) and left ventricular systolic ...

European Heart Journal, Pitt, Bertram

Date : 01/10/2008

The mechanisms responsible for the beneficial effects of ABs in patients with HFREF continue to evolve but include: an increase in antioxidant reserves and a decrease in oxygen free radical ...

European Heart Journal, Pitt, Bertram

Date : 01/02/2009 Item size : 126211 bytes