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Over time many stroke risk stratification schema have been developed, initially with the objective to better define high-risk patients who could be subjected to an inconvenient (and potentially ...

Europace, Editorial, Ron Pisters, Jonas B. Olesen, Gregory Y.H. Lip

Date : 01/01/2012 Item size : 140103 bytes

The fear of bleeding among physicians leads to lack of prescription of oral anticoagulants, and reduces uptake, in patients who may otherwise benefit from them.1,2 Stroke risk is closely related to ...

Europace, Editorial, Pilar Gallego, Gregory Y. H. Lip, Deirdre A. Lane

Date : 01/06/2013 Item size : 150506 bytes

Numerous risk factors pre-dispose to atrial fibrillation (AF), namely, hypertension, heart failure, increasing age, diabetes mellitus, and vascular disease.1 Due to the ageing population and the ...

Europace, Editorial, Jonas Bjerring Olesen, Gregory Y.H. Lip, Deirdre A. Lane

Date : 01/08/2011

For adequate stroke prevention, most patients with non-valvular atrial fibrillation (AF) would need oral anticoagulant therapy (OAC), with either vitamin-K antagonists (VKAs) or non-vitamin-K oral ...

Europace, Editorial, Tatjana S. Potpara, Deirdre A. Lane, Gregory Y.H. Lip

Date : 01/04/2015

Atrial fibrillation (AF) is the commonest cardiac rhythm disorder and is associated with an increased risk of mortality and morbidity from stroke and thromboembolism. Several NOACs now exist, ...

Europace, Editorial, Torben Bjerregaard Larsen

Date : 01/02/2015

Methods and results In isolated rat atrial fibroblasts, thrombin enhanced the phosphorylation of the pro-fibrotic signalling molecules Akt and Erk and increased the expression of transforming growth ...

European Heart Journal, BASIC SCIENCE, Henri M.H. Spronk, Anne Margreet De Jong, Sander Verheule, Hetty C. De Boer, Alexander H. Maass, Dennis H. Lau, Michiel Rienstra, Arne van Hunnik, Marion ...

Date : 01/01/2017

Vitamin K antagonists such as warfarin are highly effective for the prevention of stroke and systemic embolism in patients with AF,1 but their use is hampered by multiple food and drug interactions, ...

European Heart Journal, Hohnloser, Stefan H., Eikelboom, John W.

Date : 01/08/2012

In the last two centuries, with an ageing population and the advance of atherosclerosis, an overly active coagulation system has become a liability for the older individual because it can lead to ...

European Heart Journal, Moser, Martin, Bode, Christoph

Date : 01/11/2011 Item size : 130701 bytes

Physicians with a passion for pharmacokinetics, and especially food and drug interactions, may have been happily engaged with the drug, but others who want to help their patients with minimum ...

European Heart Journal

Date : 21/07/2014 Item size : 151321 bytes

Christian Tobias TORP-PEDERSEN (Aalborg, Denmark) 14:22 1204 My patient on a oral anticoagulant presents with an ischaemic stroke, and is being considered for thrombolysis. Jonas OLDGREN (Uppsala, ...

Practical aspects on stroke prevention in atrial fibrillation - what to do in 2015?

Date : 23/06/2015 Item size : 87022 bytes