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Tel: +31 50 361 2355, Fax: +31 50 361 5525, Email: Search for more papers by this author Abstract Aims Liver X receptors (LXRs) transcriptionally regulate inflammation, ...

European Journal of Heart Failure, Cannon, Megan V., Yu, Hongjuan, Candido, Wellington M., Dokter, Martin M., Lindstedt, Eva‐Lotte, Silljé, Herman H.W., van Gilst, Wiek H., de Boer, Rudolf A.

Date : 01/03/2015 Item size : 153443 bytes

The growth in fibrous tissue content is based on the maintained proliferative potential of fibroblasts (largely absent in myocytes of the adult heart [3]), and the synthesis of extra-cellular matrix ...

Cardiovascular Research, Research Article, Patrizia Camelliti, Thomas K. Borg, Peter Kohl

Date : 01/01/2005 Item size : 422066 bytes

Abstract Objective: The aim of this study was to determine whether chronic β-adrenergic receptor (β-AR) stimulation induces proliferation of human cardiac fibroblasts and to investigate the ...

Cardiovascular Research, Original Article, Neil A Turner, Karen E Porter, William H.T Smith, Hazel L White, Stephen G Ball, Anthony J Balmforth

Date : 01/03/2003 Item size : 274405 bytes

In adults, EPO is produced primarily in the kidney via an oxygen-sensing mechanism and stimulates erythroid progenitors in the bone marrow to increase red blood cell mass. The therapeutic relevance ...

Cardiovascular Research, Editorial, Qingping Feng

Date : 01/09/2006 Item size : 169639 bytes

Conclusions: AT1 blockade is associated with a significant decrease in cardiac fibrosis in treated post-MI rats, and this trend is positively correlated to a significant decrease in immunoreactive PH ...

Cardiovascular Research, Original Article, Haisong Ju, Shufang Zhao, Davinder S Jassal, Ian M.C Dixon

Date : 01/08/1997

Abstract Aims The Wnt/frizzled (Fzd) signal transduction cascade has been implicated in the proliferation, differentiation, and migration of many cell types, but the role of this pathway in cardiac ...

Cardiovascular Research, Original Article, Hilde Laeremans, Sander S. Rensen, Harry C.J. Ottenheijm, Jos F.M. Smits, W. Matthijs Blankesteijn

Date : 01/08/2010

[...]in vivo post-infarction treatment with the broadband LOX inhibitor β-aminopropionitrile or, selectively, with a neutralizing antibody against the canonical LOX isoform attenuated collagen ...

Cardiovascular Research, Original Article, José González-Santamaría, María Villalba, Oscar Busnadiego, Marina M. López-Olañeta, Pilar Sandoval, Jessica Snabel, Manuel ...

Date : 01/01/2016

Introduction The E2F transcription factors are best characterized for their roles in cell-cycle regulation, cell growth, and cell survival.1 E2F family members regulate transcription by binding to ...

Cardiovascular Research, Cardiac biology and remodelling, Min Wu, Junlan Zhou, Min Cheng, Chan Boriboun, Dauren Biyashev, Hong Wang, Alexander Mackie, Tina Thorne, Jonathan Chou, Yiping Wu, Zhishui ...

Date : 01/12/2014

Metformin inhibited cardiac fibrosis (fibrosis area/total heart area: 0.6 ± 0.3 vs. 3.6 ± 0.9%, P < 0.01) induced by pressure overload and improved cardiac diastolic function (left ventricular ...

Cardiovascular Research, Original Article, Han Xiao, Xiaowei Ma, Wei Feng, Yongnan Fu, Zhizhen Lu, Ming Xu, Qiang Shen, Yi Zhu, Youyi Zhang

Date : 01/08/2010

[...]this is often obscured by adverse processes such as myocardial stunning injury and cardiac remodelling, i.e. ventricular hypertrophy, interstitial fibrosis, contractile dysfunction, ...

Cardiovascular Research, Editorial, Arash Haghikia, Denise Hilfiker-Kleiner

Date : 01/04/2009