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Introduction Patients with diabetes mellitus (DM) have an increased risk of coronary heart disease, and cardiovascular complications are responsible for the majority of diabetes-related deaths.1 In ...

Cardiovascular Research, ORIGINAL ARTICLES: SPOTLIGHT ON REDUCING MYOCARDIAL ISCHAEMIA/REPERFUSION INJURY, Tao Rui, Jinchao Zhang, Xuemei Xu, Yongwei Yao, Raymond Kao, Claudio M. Martin

Date : 01/05/2012 Item size : 272777 bytes

Abstract Aims Our aim was to test the hypothesis that angiotensin II receptor blockade combined with exercise training after myocardial infarction (MI) could attenuate post-MI left ventricular ...

Cardiovascular Research, Original Article, Xiaohua Xu, Wenhan Wan, Lisa Ji, Shunhua Lao, Anthony S. Powers, Weiyan Zhao, John M. Erikson, John Q. Zhang

Date : 01/06/2008 Item size : 367993 bytes

Abstract This brief review summarizes the recently obtained evidence which illustrates the beneficial effects of the endogenously produced antioxidant, melatonin, in reducing tissue damage and ...

Cardiovascular Research, Review, Russel J. Reiter, Dun-Xian Tan

Date : 01/04/2003 Item size : 397783 bytes

Abstract Despite major advances in the treatment of cardiac diseases, there is still a great need for drugs capable of counteracting the deterioration of cardiac muscle function in congestive heart ...

Cardiovascular Research, TOPICAL REVIEWS, Guido Tarone, Mara Brancaccio

Date : 01/06/2014 Item size : 771132 bytes

Bone marrow (BM) chimaera experiments showed that this effect was due to the absence of C5aR on circulating leucocytes, since a similar reduction in infarct size was observed in WT mice with ...

Cardiovascular Research, Original Article, Vince C. De Hoog, Leo Timmers, Amerik Van Duijvenvoorde, Saskia C. A. De Jager, Ben J. Van Middelaar, Mirjam B. Smeets, Trent M. Woodruff, Pieter A. ...

Date : 01/09/2014 Item size : 335513 bytes

Introduction The innate immune system plays a central role in the pathophysiology of myocardial ischaemia/reperfusion (I/R) injury and heart failure1; however, the mechanisms are unknown. Toll-like ...

Cardiovascular Research, Original Article, Tuanzhu Ha, Yulong Hu, Li Liu, Chen Lu, Julie R. McMullen, Jim Kelley, Race L. Kao, David L. Williams, Xiang Gao, Chuanfu Li

Date : 01/09/2010

Abstract Objectives: Recent studies have demonstrated that hamsters, like humans, possess both angiotensin converting enzyme (ACE)- and chymase-dependent angiotensin (Ang) II-forming pathways in ...

Cardiovascular Research, Original Article, Denan Jin, Shinji Takai, Mayumi Yamada, Masato Sakaguchi, Keiichi Kamoshita, Koichi Ishida, Yoshikazu Sukenaga, Mizuo Miyazaki

Date : 01/11/2003

Abstract Objective: Myocardial contractility is enhanced in transgenic (TG) mice with cardiac-restricted overexpression of the α1A-adrenergic receptors (α1A-AR). Methods We subjected α1A-TG ...

Cardiovascular Research, Original Article, Xiao-Jun Du, Xiao-Ming Gao, Helen Kiriazis, Xiao-Lei Moore, Ziqiu Ming, Yidan Su, Angela M. Finch, Ross A. Hannan, Anthony M. Dart, Robert M. Graham

Date : 01/09/2006

Control (n=8): no intervention at R; Ischemic preconditioning (IPC) (n=8): the LCA was occluded for 5 min followed by 10 min of R before the index occlusion; Post-con 1 (n=8): after LCA occlusion, ...

Cardiovascular Research, Original Article, Hajime Kin, Zhi-Qing Zhao, He-Ying Sun, Ning-Ping Wang, Joel S. Corvera, Michael E. Halkos, Faraz Kerendi, Robert A. Guyton, Jakob Vinten-Johansen

Date : 01/04/2004

Abstract Objective: The purpose of this study was to examine the effect of amlodipine, a long-acting calcium antagonist, on the left ventricular remodeling, including systolic and diastolic ...

Cardiovascular Research, Original Article, Takehiro Shimada, Minoru Yoshiyama, Kazuhide Takeuchi, Takashi Omura, Yasuhiko Takemoto, Shokei Kim, Hiroshi Iwao, Junichi Yoshikawa

Date : 01/03/1998