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R J Hassink1, H Nakajima2, H O Nakajima2, P A Doevendans1, L J Field2 1Department of Cardiology, University Medical Centre, Utrecht, The Netherlands 2Wells Center for Pediatric Research and Krannert ...

Heart, Original article, R J Hassink, H Nakajima, H O Nakajima, P A Doevendans, L J Field

Date : 15/07/2009

Introduction Pulmonary arterial hypertension (PAH), chronic thrombo-embolic pulmonary hypertension (CTEPH), and a variety of congenital heart diseases increase the workload of the right ...

European Journal of Heart Failure, Andersen, Asger, Povlsen, Jonas Agerlund, Bøtker, Hans Erik, Nielsen‐Kudsk, Jens Erik

Date : 01/11/2013 Item size : 162577 bytes

Methods and results In cultured neonatal mouse cardiomyocytes, deficiency of JNK1 or selective inhibition of JNK1 signalling by over-expression of a dominant negative mutant of JNK1 enhanced ...

Cardiovascular Research, Original Article, Tianqing Peng, Ting Zhang, Xiangru Lu, Qingping Feng

Date : 01/03/2009 Item size : 315319 bytes

Abstract Aims As oral corticosteroids have a beneficial effect on muscle strength in Duchenne muscular dystrophy, it has been suggested that they may also be a useful treatment in the pathologically ...

Cardiovascular Research, Original Article, R. Bauer, G.A. MacGowan, A. Blain, K. Bushby, V. Straub

Date : 01/09/2008 Item size : 320429 bytes

Results Runx1 is expressed within the BZ and remote LV myocardium in a mouse model of MI and its expression negatively correlates with cardiac function measured by pressure-volume (PV) loop ...

Heart, Abstracts, CS McCarroll, W He, KK Foote, K Nather, C Fattah, EBA Elliott, A Cochrane, P Bowman, M Bell, T Kubin, T Braun, SA Nicklin, ER Cameron, CM Loughrey

Date : 01/11/2015

[...]altered expression of PLB and SLN has been reported in many cardiac diseases. [...]SERCA2a is a major regulator of intracellular Ca2+ homeostasis, and changes in the expression and activity of ...

Cardiovascular Research, Review, Muthu Periasamy, Poornima Bhupathy, Gopal J. Babu

Date : 15/01/2008 Item size : 520644 bytes

To investigate the role of PLCγ1 in endotoxemia in vivo, wild-type and heterozygous PLCγ1 knockout (PLCγ1+/ mice were pre-treated with either U73122, or its inactive analog U73343, or ...

Cardiovascular Research, Original Article, Tianqing Peng, E Shen, Jue Fan, Yan Zhang, J. Malcolm O. Arnold, Qingping Feng

Date : 01/04/2008

Abstract Objectives: The role of p38 mitogen-activated protein kinase (MAPK) activation in lipopolysaccharide (LPS)-induced myocardial dysfunction has not been clearly defined. TNF-α mRNA and ...

Cardiovascular Research, Original Article, Tianqing Peng, Xiangru Lu, Ming Lei, Gordon W Moe, Qingping Feng

Date : 01/10/2003

Abstract Aims Severe sustained bradycardia may cause acute and possibly chronic congestive heart failure (CHF). The aim of this study was to investigate acute and chronic effects of complete heart ...

Europace, COMPLETE HEART BLOCK, S. Gizurarson, M. Lorentzon, T. RÃ¥munddal, F. Waagstein, L. Bergfeldt, E. Omerovic

Date : 01/06/2007

Despite major advances in the understanding of cardiovascular physiology and pathophysiology and the development of new therapies in the 20th century, cardiovascular disease is projected to become ...

Cardiovascular Research, Review, Ajay M Shah, Steven J Sollott, Edward G Lakatta

Date : 01/07/1998