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Gradually over the last 12 years dogs and cats, the classical experimental animals in cardiovascular sciences, became unfashionable for a variety of reasons, some of them nonscientific (i.e., new ...

Cardiovascular Research, Leading Article, Wolfgang Schaper, Bernd Winkler

Date : 01/07/1998 Item size : 155344 bytes

Netrin-1 has also been shown to exert a cardioprotective action in the context of ischaemiareperfusion injury following myocardial infarction. [...]urinary netrin-1 levels rise in response to acute ...

Cardiovascular Research, Review, Kerry Layne, Albert Ferro, Gabriella Passacquale

Date : 01/09/2015 Item size : 381577 bytes

There is mounting evidence that thrombin acts as a powerful modulator of many processes like regulation of vascular tone, permeability, migration and proliferation of VSMC, recruitment of monocytes ...

Cardiovascular Research, Review, Julian Ilcheff Borissoff, Henri M.H. Spronk, Sylvia Heeneman, Hugo ten Cate

Date : 01/06/2009 Item size : 584450 bytes

Based on these observations and the biological effects induced by ET-1, including profound vasoconstriction, pro-inflammatory actions, mitogenic and proliferative effects, stimulation of free radical ...

Cardiovascular Research, Review, Felix Böhm, John Pernow

Date : 01/10/2007 Item size : 470334 bytes

The implication of chronic inflammation in the pathogenesis of atherosclerotic lesions was initially proposed by Virchow9 in the mid-nineteenth century and evolved over the next century into the ...

Cardiovascular Research, Review, Stavros Apostolakis, Konstantina Vogiatzi, Virginia Amanatidou, Demetrios A. Spandidos

Date : 01/12/2009 Item size : 388218 bytes

Levels of CRP are consistently associated with cardiovascular disease (CVD) and predict myocardial infarctions and stroke. Since CRP is present in the atherosclerotic lesion, it may actively ...

Cardiovascular Research, Review, Elaine Paffen, Moniek P.M. deMaat

Date : 01/07/2006 Item size : 473048 bytes

Results: After 4 months, the GTG-injected mice were significantly overweight (mean body weight (g): 33±2.11 vs. 23±0.24 and 17±0.31 in control and food-restricted mice, respectively), obese, ...

Cardiovascular Research, Original Article, L.G Lyngdorf, S Gregersen, A Daugherty, E Falk

Date : 01/10/2003 Item size : 260058 bytes

Abstract Several pathologies of the cardiovascular system are associated with an augmented production of nitric oxide and/or superoxide-derived oxidants and/or alteration in the antioxidant ...

Cardiovascular Research, Review, Gonzalo Peluffo, Rafael Radi

Date : 15/07/2007 Item size : 511451 bytes

An analysis of the underlying causes identifies improvements in quality of care and treatment as a major cause, accounting from 50 up to 75% of the success depending on the study samples, the ...

Cardiovascular Research, VIEWPOINT EDITORIAL, Karin R. Sipido, Alain Tedgui, Steen D. Kristensen, Gerard Pasterkamp, Heribert Schunkert, Martin Wehling, Philippe G. Steg, Wolfgang Eisert, Frank ...

Date : 01/08/2009 Item size : 477459 bytes

In the elderly inflammatory markers are non-specific measures of health and predict both disability and mortality even in the absence of clinical cardiovascular disease. [...]it is possible that, in ...

Cardiovascular Research, Review, Stephen B. Kritchevsky, Matteo Cesari, Marco Pahor

Date : 01/05/2005 Item size : 522341 bytes