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[...]pharmacological strategies aimed at the prevention and treatment of acute cardiovascular disease thus far mainly focus on the reduction of atherosclerotic burden (e.g. by preventative strategies ...

Cardiovascular Research, Levi, Marcel, Stroes, Erik

Date : 01/06/2008 Item size : 129316 bytes

The current issue of the European Heart Journal focuses on a novel area of research, i.e. the function of microribonucloidacids (miRNAs). miRNAs are short, usually around 22-nucleotide-long ...

European Heart Journal, Lüscher, Thomas F.

Date : 01/12/2014 Item size : 112207 bytes

Statins block hydroxymethylglutaryl (HMG)-CoA reductase, which is a rate-limiting enzyme not only for the production of cholesterol via the squalene pathway but also for the generation of several ...

European Heart Journal, Ray, Kausik K.

Date : 21/06/2013 Item size : 148136 bytes

In particular, it has been shown that SIRT1 activation improves endothelial dysfunction and suppresses vascular inflammation, two central pathophysiological processes involved in the initiation and ...

Cardiovascular Research, Gracia-Sancho, Jorge, Villarreal, Guadalupe, Zhang, Yuzhi, García-Cardeña, Guillermo

Date : 01/02/2010 Item size : 214564 bytes

Introduction: Interactions between vascular endothelial cells (ECs) and perivascular cells (like vascular smooth muscle cells and pericytes) are essential in the regulation of vascular remodelling ...

Cardiovascular Research

Date : 01/07/2016

Animal as well as human studies have shown beneficial changes in biological phenomena related to cardiovascular health after the consumption of polyphenol-rich foods such as cocoa, red wine, tea, and ...

Cardiovascular Research, Páramo, José A.

Date : 01/07/2008

In chronic heart failure, the aldosterone activity is inappropriately elevated, causing salt retention; it has been argued that the resulting calcium wasting causes secondary ...

Cardiovascular Research, Tomaschitz, Andreas, Ritz, Eberhard, Pieske, Burkert, Fahrleitner-Pammer, Astrid, Kienreich, Katharina, Horina, Jörg H., Drechsler, Christiane, März, Winfried, Ofner, ...

Date : 01/04/2012 Item size : 552782 bytes

The review article from Frueh et al.8 embraces this complexity and describes the current challenges of large data sets and the application of systems biology in the exploration of the effects of ...

Cardiovascular Research, Evans, Paul C., Kwak, Brenda R.

Date : 15/07/2013

Abstract Objective: Endothelial-derived nitric oxide (NO), by increasing cGMP, is a major physiological regulator of vascular tone and of vascular smooth muscle cell (VSMC) adhesion, chemotaxis, and ...

Cardiovascular Research, Isenberg, Jeff S., Wink, David A., Roberts, David D.

Date : 01/09/2006 Item size : 342867 bytes

Abstract Aims Visfatin is a novel adipokine whose plasma concentrations are altered in obesity and obesity-related disorders; these states are associated with an increased incidence of cardiovascular ...

Cardiovascular Research, Adya, Raghu, Tan, Bee K., Punn, Anu, Chen, Jing, Randeva, Harpal S.

Date : 01/05/2008