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Ehjournal

Not surprisingly, the authors observed that presumably more active variants of NPC1L1 occur with higher serum cholesterol levels.1 The same variants increased the odds for vascular disease but had ...

European Heart Journal, Schunkert, Heribert

Date : 01/07/2015 Item size : 191186 bytes
Ehjournal

Abstract Aims To compare the efficacy [low-density lipoprotein cholesterol (LDL-C) lowering] and safety of alirocumab, a fully human monoclonal antibody to proprotein convertase subtilisin/kexin 9, ...

European Heart Journal, Cannon, Christopher P., Cariou, Bertrand, Blom, Dirk, McKenney, James M., Lorenzato, Christelle, Pordy, Robert, Chaudhari, Umesh, Colhoun, Helen M.

Date : 14/05/2015 Item size : 271307 bytes
Ehjournal

During the last decade, the evidence that statins have potent effects in reducing death and myocardial infarction in patients following acute coronary syndromes has become overwhelming, both in ...

European Heart Journal, Herrler, Tanja, Böhm, Michael, Heeschen, Christopher

Date : 01/09/2008 Item size : 131656 bytes
Ehjournal

[...]statin treatment also reduced the risk for cardiovascular events and all-cause mortality. See page 1775 for the editorial comment on this article (doi:10.1093/eurheartj/eht124) Introduction In ...

European Heart Journal, Biere-Rafi, Sara, Hutten, Barbara A., Squizzato, Alessandro, Ageno, Walter, Souverein, Patrick C., de Boer, Anton, Gerdes, Victor E.A., Büller, Harry R., Kamphuisen, Pieter ...

Date : 21/06/2013
Ehjournal

First among them are three lifestyle targets: smoking cessation, switch to a healthy Mediterranean-style diet, and regular physical activity. [...]are six biomedical targets: blood pressure ...

European Heart Journal, Boland, B, Goderis, G

Date : 01/05/2004
Ehjournal

Cholesterol lowering with statin therapy has been shown to reduce cardiovascular events in a variety of patient categories, ranging from patients with established cardiovascular disease to high-risk ...

European Heart Journal, Holdaas, Hallvard

Date : 01/02/2008 Item size : 111670 bytes
Ehjcardiovascrec

Commentary on Evolocumab and clinical outcomes in patients with cardiovascular disease by Sabbatine et al., N Engl J Med 2017.1 The results of the Further Cardiovascular Outcomes Research with PCSK9 ...

Cardiovascular Research, Landmesser, Ulf

Date : 01/07/2017
Ehjcardiovascrec

Abstract Patients with increased cholesterol levels are at increased risk to experience cardiovascular events and to die from vascular disease. Statins have been proven to effectively reduce ...

Cardiovascular Research, van der Harst, Pim, Voors, Adriaan A., van Gilst, Wiek H., Böhm, Michael, van Veldhuisen, Dirk J.

Date : 01/08/2006 Item size : 374976 bytes
Ehjournal

A 160 309-person participant level meta-analysis of 54 prospective studies found the relationship between log-CRP concentration and cardiovascular disease (CVD) events to be linear, with a 2.5-fold ...

European Heart Journal, Hingorani, Aroon D., Sofat, Reecha, Morris, Richard W., Whincup, Peter, Lowe, Gordon D., Mindell, Jennifer, Sattar, Naveed, Casas, Juan P., Shah, Tina

Date : 01/09/2012
Ehjournal

Prospective randomized studies testing the impact of a functional food on cardiovascular events are rare. [...]Kromhout et al. are to be congratulated on their important Alpha Omega trial that ...

European Heart Journal, Laufs, Ulrich, Schirmer, Stephan H.

Date : 01/07/2012