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The demonstration that gene therapy can improve collateral function presents one of the solutions to the conundrum, since gene therapy can be considered a sophisticated form of a sustained delivery ...

Cardiovascular Research, Review, Stephen E. Epstein, Shmuel Fuchs, Yi Fu Zhou, Richard Baffour, Ran Kornowski

Date : 16/02/2001 Item size : 488164 bytes

Heart failure (HF) remains an important public health problem, which is increasing in incidence and prevalence. [...]the recent PARADIGM-HF study[2] identified the first new class of drugs for the ...

European Journal of Heart Failure, Gold, Michael R., van Veldhuisen, Dirk J., Mann, Douglas L.

Date : 01/02/2015 Item size : 81797 bytes

The Framingham study demonstrated that the life time risk for developing HF is one in five for both men and women.1 Evidence-based treatment of chronic HF is mainly focused on suppressing the chronic ...

European Journal of Heart Failure, Domian, Ibrahim J., Buikema, Jan W., Boer, Rudolf A., Meer, Peter

Date : 01/07/2010 Item size : 100987 bytes

Tel: +86 21 52887164, Fax: +86 21 52887164, Email: Search for more papers by this author Abstract Aims Anaemia is a frequent comorbidity in patients with chronic heart failure ...

European Journal of Heart Failure, Jin, Bo, Luo, Xinping, Lin, Haihong, Li, Jian, Shi, Haiming

Date : 01/03/2010 Item size : 139366 bytes

Abstract Multiple prospective randomized trials with implantable cardioverter defibrillators (ICDs) over the past decade have convincingly established the efficacy of ICD therapy in reducing ...

Europace, ICD, Seah Nisam, Günter Breithardt

Date : 01/06/2006 Item size : 211079 bytes

Important questions regarding vector-related limitations and suboptimal in vivo delivery systems will require expeditious attention for gene therapy to become a more widely applicable option in ...

Cardiovascular Research, Review, Peter Sinnaeve, Olivier Varenne, Désiré Collen, Stefan Janssens

Date : 01/12/1999 Item size : 488771 bytes

The backdrop: cardioprotection lost in translation Early work from Dr Braunwald's group demonstrated that the infarct size was not a predetermined entity, but could be modified by interventions ...

Cardiovascular Research, EDITORIALS: SPOTLIGHT ON LANDMARK PAPERS IN, Jakob Vinten-Johansen

Date : 01/11/2012 Item size : 210501 bytes

In the study by Marechaux et al., the authors performed a prospective multi-centre observational and cross-sectional study evaluating the presence of mitral- and/or aortic valve disease in a large ...

European Heart Journal - Cardiovascular Imaging, EDITORIALS, Bernard Cosyns, Steven Droogmans

Date : 01/02/2015

Methods and results Meta-analysis and regression of large animal studies were performed to identify sources that influenced effect size of anti-inflammatory compounds in large animal models of ...

Cardiovascular Research, Original Article, Gerardus P. J. van Hout, Sanne J. Jansen of Lorkeers, Kimberly E. Wever, Emily S. Sena, Lisanne H. J. A. Kouwenberg, Wouter W. van Solinge, Malcolm R. ...

Date : 01/02/2016

Human relevance of pre-clinical studies in stem cell therapy: systematic review and meta-analysis of large animal models of ischaemic heart disease Methods and results Random-effects meta-analysis ...

Cardiovascular Research, Original Article, Tycho I.G. van der Spoel, Sanne J. Jansen of Lorkeers, Pierfrancesco Agostoni, Eric van Belle, Mariann Gyöngyösi, Joost P.G. Sluijter, Maarten J. ...

Date : 01/09/2011