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Introduction Patients with diabetes mellitus (DM) have an increased risk of coronary heart disease, and cardiovascular complications are responsible for the majority of diabetes-related deaths.1 In ...

Cardiovascular Research, ORIGINAL ARTICLES: SPOTLIGHT ON REDUCING MYOCARDIAL ISCHAEMIA/REPERFUSION INJURY, Tao Rui, Jinchao Zhang, Xuemei Xu, Yongwei Yao, Raymond Kao, Claudio M. Martin

Date : 01/05/2012 Item size : 272777 bytes

Changes in mitochondrial morphology are regulated by the mitochondrial fusion proteins (mitofusins 1 and 2, and optic atrophy 1) and the mitochondrial fission proteins (dynamin-related peptide 1 and ...

Cardiovascular Research, REVIEWS: FOCUS ON MITOCHONDRIA IN CARDIAC DISEASE, Sang-Bing Ong, Derek J. Hausenloy

Date : 01/10/2010 Item size : 526652 bytes

KeywordsDiabetesCardiomyopathyCalcium, intracellular concentrationSR, calcium releaseTime for primary review 33 days. 1 Introduction Diabetes mellitus has been associated with cardiac disease that ...

Cardiovascular Research, Review, Jen Z Yu, Brian Rodrigues, John H McNeill

Date : 01/04/1997 Item size : 190087 bytes

Abstract Objective: This is the first part of a bipartite review that summarizes the rising knowledge on the molecular mechanisms underlying the action of advanced glycation endproducts (AGEs) and ...

Cardiovascular Research, Review, Angelika Bierhaus, Marion A Hofmann, Reinhard Ziegler, Peter P Nawroth

Date : 01/03/1998 Item size : 674303 bytes

Methods: Right atrial sections from four patient groupsnon-diabetic, insulin-dependent diabetes mellitus (IDDM), non-insulin-dependent diabetes mellitus (NIDDM) receiving glibenclamide, and NIDDM ...

Cardiovascular Research, Original Article, Ashraf Hassouna, Mahmoud Loubani, Bashir M. Matata, Alan Fowler, Nicholas B. Standen, Manuel Galiñanes

Date : 01/02/2006 Item size : 344831 bytes

Novel molecular approaches have helped to improve our understanding of the process of collateral vessel formation in recent years. Besides the process of true angiogenesis, i.e. the formation of new ...

Cardiovascular Research, Review, Johannes Waltenberger

Date : 16/02/2001 Item size : 254383 bytes

Abstract Objectives: Elevated concentrations of C-reactive protein (CRP), a non-specific acute phase reactant, and troponin I (TnI), a cardiac-specific marker of myocardial damage, have been found to ...

Cardiovascular Research, Original Article, Robbert J de Winter, Radha Bholasingh, Jeroen G Lijmer, Rudolph W Koster, Jozef P.M.C Gorgels, Yvonne Schouten, Frans J Hoek, Gerard T Sanders

Date : 01/04/1999 Item size : 230060 bytes

Abstract Objective: Abnormalities in the regulation of natriuretic peptides (NP) associated with major diseases such as hypertension, heart failure, and diabetes mellitus (DM) have been ...

Cardiovascular Research, Original Article, Thomas Walther, Heinz-Peter Schuitheiss, Carsten Tschöpe

Date : 15/08/2001 Item size : 202287 bytes

Diabetes mellitus has been shown to be associated with heart failure of unknown origin, which is termed diabetic cardiomyopathy [1]. [2]have shown that the small vessel lesions in diabetes mellitus ...

Cardiovascular Research, Review, Hideharu Hayashi, Naohisa Noda

Date : 01/04/1997 Item size : 162847 bytes

Specifically, the interaction of AGEs with vessel wall components increases vascular permeability, the expression of procoagulant activity and the generation of reactive oxygen species (ROS), ...

Cardiovascular Research, Review, Giuseppina Basta, Ann Marie Schmidt, Raffaele De Caterina

Date : 01/09/2004 Item size : 451901 bytes