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Ehjcardiovascrec

Abstract Objective: The mitogen-activated kinase kinases (MEK)-extracellular signal-regulated kinases (ERK) signaling pathway is activated by agonists like catecholamines or endothelin-1 (ET-1) and ...

Cardiovascular Research, Original Article, Felix Münzel, Ulrike Mühlhäuser, Wolfram-Hubertus Zimmermann, Michael Didié, Karin Schneiderbanger, Pia Schubert, Sven Engmann, Thomas ...

Date : 01/12/2005
Ehjcardiovascrec

Myocardial hypertrophy is either a primary disease of the heart as found for genetic cardiomyopathies (hypertrophic or dilated), or an adaptative response secondary to, for instance, hemodynamic ...

Cardiovascular Research, Editorial, Stéphane Baudet

Date : 01/04/2000
Ehjcardiovascrec

KeywordsCardiomyopathyHeart failureProtein kinasesSignal transductionTime for primary review 29 days. 1 Introduction Heart failure is an increasingly important public health problem with a high ...

Cardiovascular Research, Original Article, Yasuchika Takeishi, Qunhua Huang, Jun-ichi Abe, Wenyi Che, Jiing-Dwan Lee, Hisaaki Kawakatsu, Brian D Hoit, Bradford.C Berk, Richard A Walsh

Date : 01/01/2002
Ehjcardiovascrec

Recently, acute activation of the Janus kinases (JAKs) and signal transducers and activators of transcription (STATs) has been observed in the heart, but whether this is sustained in ischemic heart ...

Cardiovascular Research, Original Article, Dominic C.H Ng, Naomi W Court, Cristobal G dos Remedios, Marie A Bogoyevitch

Date : 01/02/2003
Ehjcardiovascrec

Introduction Abnormal intracellular calcium (Ca2+) handling, and in particular, dysregulated Ca2+ release from the sarcoplasmic reticulum (SR), has been implicated in a range of cardiac diseases, ...

Cardiovascular Research, ORIGINAL ARTICLES: SPOTLIGHT ON T-TUBULES AND RYANODINE RECEPTOR MICRODOMAIN SIGNALLING IN CARDIAC HYPERTROPHY AND FAILURE, Anuradha Kalyanasundaram, Véronique A. Lacombe, ...

Date : 01/05/2013
Ehjournal

[...]in a recently completed large-scale clinical trial, 30% of patients with stable NYHA class II or III heart failure died during a mean follow-up period of less than 3 1/2 years; at the same time, ...

European Heart Journal, Wollert, Kai C, Drexler, Helmut

Date : 01/12/2003
Ehjcardiovascrec

Abstract Aims The Cav3.2 T-channel plays a pivotal role in inducing calcineurin/nuclear factor of activated T cell (NFAT) signalling during cardiac hypertrophy. Because calcineurin/NFAT signalling ...

Cardiovascular Research, Hsu, Shao-Chun, Chang, Ya-Ting, Chen, Chien-Chang

Date : 01/11/2013 Item size : 269374 bytes
Ehjournal

[...]in a recently completed large-scale clinical trial, 30% of patients with stable NYHA class II or III heart failure died during a mean follow-up period of less than 3 1/2 years; at the same time, ...

European Heart Journal, Wollert, Kai C, Drexler, Helmut

Date : 01/12/2003 Item size : 102862 bytes
Ehjcardiovascrec

Recently, acute activation of the Janus kinases (JAKs) and signal transducers and activators of transcription (STATs) has been observed in the heart, but whether this is sustained in ischemic heart ...

Cardiovascular Research, Ng, Dominic C.H, Court, Naomi W, dos Remedios, Cristobal G, Bogoyevitch, Marie A

Date : 01/02/2003 Item size : 300118 bytes
Ehjcardiovascrec

Time for primary review 29 days. 1 Introduction Heart failure is an increasingly important public health problem with a high mortality rate. Activation of the Gαq signaling pathway, which ...

Cardiovascular Research, Takeishi, Yasuchika, Huang, Qunhua, Abe, Jun-ichi, Che, Wenyi, Lee, Jiing-Dwan, Kawakatsu, Hisaaki, Hoit, Brian D, Berk, Bradford.C, Walsh, Richard A

Date : 01/01/2002