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Introduction Metabolic syndrome with visceral fat accumulation is a major risk factor for atherosclerotic cardiovascular disease.1 Adipose tissue produces a number of adipocytokines, such as leptin ...

Cardiovascular Research, Original Article, Kaho Watanabe, Rena Watanabe, Hanae Konii, Remina Shirai, Kengo Sato, Taka-aki Matsuyama, Hatsue Ishibashi-Ueda, Shinji Koba, Youichi Kobayashi, Tsutomu ...

Date : 01/05/2016 Item size : 368317 bytes

Uncontrolled collagen accumulation leads to arterial stenosis, while excessive collagen breakdown combined with inadequate synthesis weakens plaques thereby making them prone to rupture. Fibrillar ...

Cardiovascular Research, Review, Mark D. Rekhter

Date : 01/02/1999 Item size : 487429 bytes

There is mounting evidence that thrombin acts as a powerful modulator of many processes like regulation of vascular tone, permeability, migration and proliferation of VSMC, recruitment of monocytes ...

Cardiovascular Research, Review, Julian Ilcheff Borissoff, Henri M.H. Spronk, Sylvia Heeneman, Hugo ten Cate

Date : 01/06/2009 Item size : 584450 bytes

Levels of CRP are consistently associated with cardiovascular disease (CVD) and predict myocardial infarctions and stroke. Since CRP is present in the atherosclerotic lesion, it may actively ...

Cardiovascular Research, Review, Elaine Paffen, Moniek P.M. deMaat

Date : 01/07/2006 Item size : 473048 bytes

Simon Cuhlmann1,2, Kim van der Heiden1, Mustafa Zakkar1, Hera Chaudhury1, Le Anh Luong1, Justin Mason1, Dorian O Haskard1, Harald Carlsen3, Robert Krams2, Paul C Evans1 1BHF Cardiovascular Sciences ...

Heart, BSCR Spring 2010 Meeting Abstracts, Simon Cuhlmann, Kim van der Heiden, Mustafa Zakkar, Hera Chaudhury, Le Anh Luong, Justin Mason, Dorian O Haskard, Harald Carlsen, Robert Krams, Paul C Evans

Date : 01/09/2010

Conclusion Endothelial CD81 upregulated in early human atheroma has the potential to play a crucial role in the initial stages of atherosclerotic plaque formation by increasing monocyte adhesion ...

Cardiovascular Research, Original Article, Jakub Rohlena, Oscar L. Volger, Jaap D. van Buul, Liesbeth H.P. Hekking, Janine M. van Gils, Peter I. Bonta, Ruud D. Fontijn, Jan Andries Post, Peter L. ...

Date : 01/01/2009 Item size : 286000 bytes

KeywordsCD36VascularMonocyte/macrophagesOxLDLAtherosclerosis Time for primary review 21 days Atherosclerosis is a progressive chronic inflammatory disease characterised by a gradual thickening and ...

Cardiovascular Research, Review, Sophie Collot-Teixeira, Juliette Martin, Chris McDermott-Roe, Robin Poston, John Louis McGregor

Date : 01/08/2007 Item size : 424958 bytes

Within atherosclerotic lesions, Egr-1 is expressed in smooth muscle cells, endothelial cells, and macrophages. Since macrophages play a pivotal role in atherosclerotic lesion initiation and ...

Cardiovascular Research, Original Article, Claudia Albrecht, Michael R. Preusch, Götz Hofmann, Samuel Morris-Rosenfeld, Erwin Blessing, Michael E. Rosenfeld, Hugo A. Katus, Florian Bea

Date : 01/05/2010 Item size : 289814 bytes

Specifically, the interaction of AGEs with vessel wall components increases vascular permeability, the expression of procoagulant activity and the generation of reactive oxygen species (ROS), ...

Cardiovascular Research, Review, Giuseppina Basta, Ann Marie Schmidt, Raffaele De Caterina

Date : 01/09/2004 Item size : 451901 bytes

The review article from Frueh et al.8 embraces this complexity and describes the current challenges of large data sets and the application of systems biology in the exploration of the effects of ...

Cardiovascular Research, Editorial, Paul C. Evans, Brenda R. Kwak

Date : 15/07/2013 Item size : 192536 bytes