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HIF-1 consists of O2-regulated HIF-1α and constitutively expressed HIF-1β subunits.1 HIF-2α is a HIF-1α paralogue that is also involved in vascular responses to ischaemia.2,3 In humans, ...

Cardiovascular Research, Rey, Sergio, Semenza, Gregg L.

Date : 01/05/2010

Abstract A fundamental feature of any immune response is the movement of leucocytes from one site in the body to another to provide effector functions. [...]elucidating the molecular mechanisms ...

Cardiovascular Research, Wong, Connie H.Y., Heit, Bryan, Kubes, Paul

Date : 01/05/2010

[...]among a large array of novel therapeutic agents with anti-angiogenic activity tested in the clinical setting in the past decade, the humanized version of a murine anti-vascular endothelial ...

Cardiovascular Research, Maio, Michele, Altomonte, Maresa, Fonsatti, Ester

Date : 01/03/2006 Item size : 144306 bytes

Abstract Blood vessels alter their morphology and function in response to changes in blood flow, and their responses are based on blood flow detection by the vascular endothelium. Endothelial cells ...

Cardiovascular Research, Ando, Joji, Yamamoto, Kimiko

Date : 15/07/2013 Item size : 394042 bytes

Results: Western blot analysis revealed a strong reduction of the expression of actin and focal-adhesion plaque (FAP) proteins in HUVEC organized in tube-like structures (TLS) on soft matrigel or on ...

Cardiovascular Research, Deroanne, Christophe F., Lapiere, Charles M., Nusgens, Betty V.

Date : 16/02/2001 Item size : 309722 bytes

Abstract Objective: A subset of adult peripheral blood leukocytes functions as endothelial progenitor cells that incorporate into the vasculature in animal models of neovascularization. Methods: ...

Cardiovascular Research, Nakul-Aquaronne, Danièle, Bayle, Jacques, Frelin, Christian

Date : 01/03/2003 Item size : 201083 bytes

In an ordered and sequential manner, however, the embryo rapidly transforms into a highly vascular organism, survival being dependent on a functional, complex network of capillary plexuses and blood ...

Cardiovascular Research, Conway, Edward M., Collen, Désiré, Carmeliet, Peter

Date : 16/02/2001 Item size : 600161 bytes

Methods: Both in vitro (rat aortic ring model, cell invasion test) and in vivo (agarose bead transplantation, artificial cardiac ischemia in Sabra rats) approaches were used in the study. PMP ...

Cardiovascular Research, Brill, Alexander, Dashevsky, Olga, Rivo, Julia, Gozal, Yaacov, Varon, David

Date : 01/07/2005

Abstract Aims α-Melanocyte-stimulating hormone (α-MSH), derived from the precursor molecule pro-opiomelanocortin, exerts potent anti-inflammatory actions in the vasculature, but its role in ...

Cardiovascular Research, Rinne, Petteri, Nordlund, Wendy, Heinonen, Ilkka, Penttinen, Anna-Maija, Saraste, Antti, Ruohonen, Suvi T., Mäkelä, Satu, Vähätalo, Laura, Kaipio, Katja, Cai, ...

Date : 01/02/2013 Item size : 308228 bytes

Methods: Membrane potentials were recorded by conventional microelectrode techniques in isolated segments of small gastric arteries, the normalized diameter of which was determined from the passive ...

Cardiovascular Research, Vanheel, B, Breyne, J

Date : 01/08/2004 Item size : 262018 bytes