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The effect of TG on the proliferation and migration of human umbilical artery endothelial cells (HUVECs) was studied in parallel. In order to investigate further the role of intracellular Ca2+ pools ...

Cardiovascular Research, Original Article, N. Shukla, N. Freeman, P. Gadsdon, G.D. Angelini, J.Y. Jeremy

Date : 16/02/2001 Item size : 231661 bytes

Abstract Objective: The autonomous proliferative response of endothelial cells to hypoxia has been shown to be dependent on activation of NAD(P)H oxidase, on the cytosolic Ca2+ load, and, ...

Cardiovascular Research, Original Article, Yaser Abdallah, Dragan Gligorievski, Sascha A. Kasseckert, Lukas Dieterich, Matthias Schäfer, Christoph R. Kuhlmann, Thomas Noll, Heinrich Sauer, ...

Date : 01/02/2007 Item size : 208820 bytes

Induction of matrix metalloproteinases-14 and -2 by cyclical mechanical stretch is mediated by tumor necrosis factor-α in cultured human umbilical vein endothelial cells Results: Cyclical ...

Cardiovascular Research, Original Article, Bao-Wei Wang, Hang Chang, Shankung Lin, Peiliang Kuan, Kou-Gi Shyu

Date : 01/08/2003 Item size : 260384 bytes

Methods and Results: Using Western blot, flow cytometry and immunohistochemistry analyses, we observed that four different statins reduced IFN-γ-induced CD40 expression in human vascular cells ...

Cardiovascular Research, Original Article, Flore Mulhaupt, Christian M Matter, Brenda R Kwak, Graziano Pelli, Niels R Veillard, Fabienne Burger, Pierre Graber, Thomas F Lüscher, François Mach

Date : 01/09/2003 Item size : 301196 bytes

Abstract Objective: Nitric oxide (NO) produced in large amounts by inducible nitric oxide synthase exerts many harmful effects such as stimulation of inflammation and induction of ...

Cardiovascular Research, Original Article, Kazuhiko Takeuchi, Hiroshi Watanabe, Quang-Kim Tran, Mariko Ozeki, Daigo Sumi, Toshio Hayashi, Akihisa Iguchi, Louis J Ignarro, Kyoichi Ohashi, Hideharu ...

Date : 01/04/2004

Vascular endothelial growth factor (VEGF) is the key angiogenic growth factor, because it regulates all steps required for angiogenesis, i.e. induces endothelial cell proliferation and migration, ...

Cardiovascular Research, Original Article, Revu Ann Alexander, Gerald W. Prager, Judit Mihaly-Bison, Pavel Uhrin, Stefan Sunzenauer, Bernd R. Binder, Gerhard J. Schütz, Michael Freissmuth, ...

Date : 01/04/2012

Introduction Unlike the network of blood vessels, the lymphatic vessels form a blind-ended transit route, carrying the protein rich lymph from the interstitium back into the blood circulation, and ...

Cardiovascular Research, Original Article, Andrew V. Benest, Steven J. Harper, Seppo Yla Herttuala, Kari Alitalo, David O. Bates

Date : 01/05/2008

Abstract Background To investigate how endothelial cells transduce intracellular signals in response to laminar shear stress (SS), we made use of the papilloma virus oncoprotein E6 which interacts ...

Cardiovascular Research, Original Article, Stefania Mattiussi, Kazue Matsumoto, Barbara Illi, Fabio Martelli, Maurizio C. Capogrossi, Carlo Gaetano

Date : 01/06/2006

Mice lacking the adaptor protein p66shc have increased resistance to oxidative stress and a 30% increase in life span.1 In the vasculature, p66shc plays an important role in endothelial dysfunction ...

Cardiovascular Research, Original Article, Sang Ki Lee, Jae In Chung, Myoung Soo Park, Hee Kyoung Joo, Eun Ji Lee, Eun Jung Cho, Jin Bong Park, Sungwoo Ryoo, Kaikobad Irani, Byeong Hwa Jeon

Date : 01/08/2011

Treatment of DZ animals with either WR 1339 (inhibits circulating TG breakdown) or N6-cyclopentyladenosine (inhibits adipose tissue lipolysis) decreased DZ induced augmentation of cardiac ...

Cardiovascular Research, Original Article, Thomas Pulinilkunnil, Dake Qi, Sanjoy Ghosh, Claudia Cheung, Patsy Yip, Jospy Varghese, Ashraf Abrahani, Roger Brownsey, Brian Rodrigues

Date : 01/09/2003