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Transcription factors and their target elements in the genome regulate the expression of genes during development and in response to extracellular signals in a cell type-specific and quantitative ...

Cardiovascular Research, Review, Birgit E.J Teunissen, Marti F.A Bierhuizen

Date : 01/05/2004 Item size : 413499 bytes

Methods: The patterns of expression of Tbx3, and of Cx40, Cx43, and Nppa, which are markers for atrial and ventricular chamber-type myocardium in the developing heart, were analyzed in mice by in ...

Cardiovascular Research, Original Article, Willem M.H Hoogaars, Alessandra Tessari, Antoon F.M Moorman, Piet A.J de Boer, Jaco Hagoort, Alexandre T Soufan, Marina Campione, Vincent M Christoffels

Date : 01/06/2004 Item size : 294462 bytes

Introduction A clear association between adverse intrauterine environment and increased risk of heart disease later in life has been demonstrated in recent epidemiological and animal studies.14 A ...

Cardiovascular Research, Original Article, Andrew J. Patterson, Daliao Xiao, Fuxia Xiong, Brandon Dixon, Lubo Zhang

Date : 01/02/2012 Item size : 322301 bytes

Compartmentalization into chambers is achieved by intervening and flanking valves and septa, respectively, that prevent the reflux and separate the flows of blood containing low- and high-oxygen ...

Cardiovascular Research, REVIEWS: SPOTLIGHT ON CARDIAC DEVELOPMENT, Franziska Greulich, Carsten Rudat, Andreas Kispert

Date : 15/07/2011 Item size : 459505 bytes

A few hours later (PS5), the rostral half of the primitive streak, with the exception of the node, contains the prospective cardiogenic cells10 (Figure 1), and also the cells that are going to ...

Cardiovascular Research, REVIEWS: SPOTLIGHT ON CARDIAC DEVELOPMENT, Carmen López-Sánchez, Virginio García-Martínez

Date : 15/07/2011 Item size : 546972 bytes

Role of Ca2+/calmodulin-dependent protein kinase II in cardiac hypertrophy and heart failure Abstract Ca2+/calmodulin-dependent protein kinase II (CaMKII), a critical transducer of Ca2+ signaling, ...

Cardiovascular Research, Review, Tong Zhang, Joan Heller Brown

Date : 15/08/2004 Item size : 465186 bytes

Abstract Aims The inflammatory responses of monocytes/macrophages and the stimulation of lipid uptake into these cells by oxidized low density lipoprotein (oxLDL) are critical to the initiation and ...

Cardiovascular Research, Original Article, Ting Chen, Zhouqing Huang, Liansheng Wang, Yue Wang, Feizhen Wu, Shu Meng, Changqian Wang

Date : 01/07/2009 Item size : 300119 bytes

The transcription factor complex hypoxia-inducible factor 1 (HIF-1) has been recognized as the master regulator that mediates the adaptational genetic response to ensure restoration of energy ...

Cardiovascular Research, Review in Review Focus Series on Hypoxia and the Pulmonary Circulation, Joachim Fandrey, Thomas A. Gorr, Max Gassmann

Date : 01/09/2006 Item size : 442327 bytes

In this review, we summarize the evidence for and against the PKC hypothesis of preconditioning, discuss the important technical limitations currently hampering PKC research, and suggest new ...

Cardiovascular Research, Review, Boris Z. Simkhovich, Karin Przyklenk, Robert A. Kloner

Date : 01/10/1998 Item size : 497847 bytes

Abstract The endocrine function of the heart was shown by the identification of a potent inhibitor of renal tubular NaCl reabsorbtion, atrial natriuretic peptide/factor (ANP), in atrial ...

Cardiovascular Research, Review, Arjan C. Houweling, Marcel M. van Borren, Antoon F.M. Moorman, Vincent M. Christoffels

Date : 01/09/2005 Item size : 428573 bytes