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Edited by Kalliopi Pilichou PhD, Cristina Basso MD, PhD, Genetics and Pathology, Padua University, Italy Background ARVC is a genetically determined cardiomyopathy caused mainly by rare genetic ...

Date : 01/10/2019

In this non-systematic review of the literature, we first present the definition of miRNAs and their action at the cellular level. Despite the complexity and challenges, it is crucial to identify ...

Date : 01/11/2018 Item size : 43252 bytes

Genome-wide association studies (GWAS), performed to understand the complex genetic basis for various diseases and traits, have led to the identification of thousands of genomic loci with roles in ...

Cardiovascular Research, Civelek, Mete, Erdmann, Jeanette

Date : 01/09/2019 Item size : 4416 bytes

The transcription factor myocyte enhancer factor 2 (MEF2) is essential for the cardiac gene regulatory network, and increasing evidence suggests its role in pathological cardiac remodelling, although ...

Cardiovascular Research, Filomena, Maria Carmela, Bang, Marie-Louise

Date : 01/09/2018 Item size : 4416 bytes

Abstract Present throughout the vasculature, endothelial cells (ECs) are essential for blood vessel function and play a central role in the pathogenesis of diverse cardiovascular diseases. An ...

Cardiovascular Research, Monteiro, João P, Bennett, Matthew, Rodor, Julie, Caudrillier, Axelle, Ulitsky, Igor, Baker, Andrew H

Date : 01/10/2019 Item size : 4416 bytes

Abstract Aims Delayed re-endothelialization after balloon angioplasty in patients with coronary or peripheral artery disease impairs vascular healing and leads to neointimal proliferation. In the ...

Cardiovascular Research, Sonnenschein, Kristina, Fiedler, Jan, Pfanne, Angelika, Just, Annette, Mitzka, Saskia, Geffers, Robert, Pich, Andreas, Bauersachs, Johann, Thum, Thomas

Date : 01/10/2019 Item size : 4416 bytes

Methods and results In Fibulin-4R/R mice, the extracellular matrix protein Fibulin-4 is 4-fold reduced, resulting in progressive ascending aneurysm formation and early death around 3 months of ...

Cardiovascular Research, van der Pluijm, Ingrid, Burger, Joyce, van Heijningen, Paula M, IJpma, Arne, van Vliet, Nicole, Milanese, Chiara, Schoonderwoerd, Kees, Sluiter, Willem, Ringuette, ...

Date : 01/11/2018 Item size : 4416 bytes

The HCA aims to describe and define the complete cellular landscape of the human body ( By analogy to the Human Genome Project, the HCA aims to map cells of the ...

Cardiovascular Research, Noseda, Michela, Harding, Sian Elizabeth

Date : 01/10/2018 Item size : 166214 bytes

Aims Epigenetics may mediate the effects of environmental risk factors on disease, including heart disease. [...]measuring the DNA methylome offers the opportunity to identify novel disease ...

Cardiovascular Research, Pan, Sun, Lai, Hao, Shen, Yiru, Breeze, Charles, Beck, Stephan, Hong, Tao, Wang, Chunsheng, Teschendorff, Andrew E.

Date : 01/05/2017 Item size : 410762 bytes