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P76Notch signaling up-regulation in diabetic epicardial adipose-tissue stem cells and angiogenic function Purpose: Type 2 diabetes mellitus patients have an increased risk of developing ...

Cardiovascular Research, Bejar, MT, Ferrer-Lorente, R, Badimon, L

Date : 15/07/2014 Item size : 102400 bytes

Purpose: High LDL-cholesterol plasma levels constitute an independent risk factor for the pathogenesis of atherothrombotic cardiovascular (CV) disease. Methods: Exosomes were isolated from ...

Cardiovascular Research, Suades, R, Padro, T, Alonso, R, Mata, P, Badimon, L

Date : 15/07/2014 Item size : 87876 bytes

Purpose: Tissue factor (TF)-mediated signaling regulates gene expression and protein synthesis leading to alterations in cell function. Recently we have demonstrated in microvascular endothelial ...

Cardiovascular Research, Arderiu, G, Pena, E, Aledo, R, Badimon, L

Date : 15/07/2014 Item size : 90504 bytes

Methods: Myocardial damage and LRP5 and Wnt signalling proteins expression levels were measured in in vivo myocardial infarction (MI) models in LRP5-/- mice and in human dyslipidemic hearts from ...

Cardiovascular Research, Borrell-Pages, M, Romero, C, Casani, L, Vilahur, G, Badimon, L

Date : 15/07/2014 Item size : 94356 bytes

Purpose: The triglyceride (TG) content in the human heart is increased in insulin resistance-related diseases. The distribution of LDL-induced intracellular lipid accumulation was assessed by ...

Cardiovascular Research, Llorente-Cortes, V, Cal, R, Revuelta Lopez, E, Julve, J, Rull, A, Martinez-Bujidos, M, Perez-Cuellar, M, Badimon, L, Sanchez Quesada, JL

Date : 15/07/2014

Purpose: Small non-coding microRNAs (miRNAs), that post-transcriptionally regulate gene expression, have emerged as key regulators of molecular pathways that may critically control monocyte ...

Cardiovascular Research, Escate, R, Padro, T, Badimon, L

Date : 15/07/2014 Item size : 102789 bytes