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Ehjcardiovascrec

Abstract Cardiac hypertrophy and fibrosis are two closely related adaptive response mechanisms of the myocardium to mechanical, metabolic, and genetic stress that finally contribute to the ...

Cardiovascular Research, SPOTLIGHT REVIEWS: SPOTLIGHT ON HETEROCELLULAR SIGNALLING AND CROSSTALK IN THE HEART IN ISCHAEMIA AND HEART FAILURE, Janika Viereck, Claudia Bang, Ariana Foinquinos, Thomas ...

Date : 01/05/2014 Item size : 769285 bytes
Ehjcardiovascrec

Treatment of cells with the MAPK inhibitor PD98059 blocked the E2-dependent repression of hMMP-2 promoter activity as well as the endogenous MMP-2 mRNA levels in both human fibroblast cells and rat ...

Cardiovascular Research, Original Article, Shokoufeh Mahmoodzadeh, Elke Dworatzek, Stephan Fritschka, Thi Hang Pham, Vera Regitz-Zagrosek

Date : 01/03/2010 Item size : 277481 bytes
Heart

H-H Chao1,*, J-J Chen3,**, C-H Chen4,***, H Lin6, C-F Cheng4, W-S Lian4, Y-L Chen3,**, S-H Juan1, J-C Liu1,***, J-Y Liou2, P Chan1,***, T-H Cheng5 1Graduate Institute of Medical Science, Taipei ...

Heart, Basic research, H-H Chao, J-J Chen, C-H Chen, H Lin, C-F Cheng, W-S Lian, Y-L Chen, S-H Juan, J-C Liu, J-Y Liou, P Chan, T-H Cheng

Date : 01/05/2005
Ejhf

Tel: +31 50 361 2355, Fax: +31 50 361 5525, Email: r.a.de.boer@umcg.nl Search for more papers by this author Abstract Aims Liver X receptors (LXRs) transcriptionally regulate inflammation, ...

European Journal of Heart Failure, Cannon, Megan V., Yu, Hongjuan, Candido, Wellington M., Dokter, Martin M., Lindstedt, Eva‐Lotte, Silljé, Herman H.W., van Gilst, Wiek H., de Boer, Rudolf A.

Date : 01/03/2015 Item size : 153443 bytes
Ehjcardiovascrec

Abstract Objective: Reactive oxygen species (ROS) such as superoxide have been linked to the hypertrophic response of the heart to stimuli including angiotensin II (AngII), mechanical stretch, and ...

Cardiovascular Research, Original Article, Adrienne Laskowski, Owen L. Woodman, Anh H. Cao, Grant R. Drummond, Tanneale Marshall, David M. Kaye, Rebecca H. Ritchie

Date : 01/10/2006 Item size : 316495 bytes
Ehjcardiovascrec

Abstract Aims MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression at the post-transcriptional level by either degradation or translational repression of a target mRNA. [...]we ...

Cardiovascular Research, Original Article, Sashwati Roy, Savita Khanna, Syed-Rehan A. Hussain, Sabyasachi Biswas, Ali Azad, Cameron Rink, Surya Gnyawali, Shani Shilo, Gerard J. Nuovo, Chandan K. Sen

Date : 01/04/2009 Item size : 310801 bytes
Ehjcardiovascrec

Abstract The reninangiotensin system (RAS) and transforming growth factor-β1 (TGF-β1) play a pivotal role in the development of cardiac hypertrophy and heart failure. Recent studies indicate ...

Cardiovascular Research, Review, Stephan Rosenkranz

Date : 15/08/2004 Item size : 492196 bytes
Ehjcardiovascrec

To test this hypothesis, the effect of mechanical load on the activation of extracellular signal-regulated kinase (ERK) 1/2, p46/54JNK, and p38MAPK was examined in rat cardiac ...

Cardiovascular Research, Original Article, Jenny Papakrivopoulou, Gisela E Lindahl, Jill E Bishop, Geoffrey J Laurent

Date : 01/03/2004
Ehjcardiovascrec

Excess deposition of cardiac ECM (fibrosis) has been associated with the pathophysiological mechanical overload of the heart. [...]the role of cardiac fibroblasts in sensing integrating and ...

Cardiovascular Research, Review, Deidre MacKenna, Sonya R. Summerour, Francisco J. Villarreal

Date : 01/05/2000
Ehjcardiovascrec

The reninangiotensin system (RAS) is activated in the pressure-overloaded myocardium and has a major role in mediating both hypertrophy and remodelling of the heart.1 Several clinical and ...

Cardiovascular Research, Original Article, Suresh K. Verma, Hind Lal, Honey B. Golden, Fnu Gerilechaogetu, Manuela Smith, Rakeshwar S. Guleria, Donald M. Foster, Guangrong Lu, David E. Dostal

Date : 01/04/2011