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Ehjcardiovascrec

The medial VSMC is the organizer of the inwardly directed angiogenic response arising from the adventitia by overexpressing vascular endothelial growth factor in response to lipid-stimulated ...

Cardiovascular Research, REVIEWS: SPOTLIGHT ON SMOOTH MUSCLE CELLS AND VASCULAR DISEASES, Patrick Lacolley, Véronique Regnault, Antonino Nicoletti, Zhenlin Li, Jean-Baptiste Michel

Date : 15/07/2012 Item size : 569256 bytes
Ehjcardiovascrec

The development and structure of blood vessels are highly adapted to haemodynamic forces, such as shear stress, cyclic stretch, and circumferential wall stress, generated by the conductance of ...

Cardiovascular Research, SPOTLIGHT REVIEWS: SPOTLIGHT ON BIOMECHANICAL FACTORS IN CARDIOVASCULAR DISEASE, Peter Neth, Maliheh Nazari-Jahantigh, Andreas Schober, Christian Weber

Date : 15/07/2013 Item size : 558042 bytes
Ehjcardiovascrec

Methods: Shear stress and statin effects in combination with TNF-α were determined in human umbilical vein endothelial cells by quantitative measurements of the steady-state levels and stability ...

Cardiovascular Research, Original Article, Johannes V. van Thienen, Joost O. Fledderus, Rob J. Dekker, Jakub Rohlena, Gerben A. van IJzendoorn, Neeltje A. Kootstra, Hans Pannekoek, Anton J.G. ...

Date : 01/11/2006 Item size : 296044 bytes
Ehjcardiovascrec

Stearoyl-CoA desaturase-1 (SCD1), which catalyzes the biosynthesis of monounsaturated fatty acids, affects the lipid composition and fluidity of the cell membrane. [...]we examined the effect of ...

Cardiovascular Research, Original Article, Xiaomei Qin, Jianwei Tian, Peng Zhang, Yanbo Fan, Li Chen, Youfei Guan, Yi Fu, Yi Zhu, Shu Chien, Nanping Wang

Date : 01/06/2007 Item size : 298015 bytes
Ehjcardiovascrec

Abstract Objectives: The molecular mechanisms underlying the relationship between elevated plasma concentrations of triglyceride-rich lipoproteins and coronary artery disease remain uncertain. In ...

Cardiovascular Research, Original Article, G.D. Norata, A. Pirillo, E. Callegari, A. Hamsten, A.L. Catapano, P. Eriksson

Date : 01/07/2003 Item size : 320426 bytes
Heart

BAS/BSCR46 X-box binding protein 1 splicing triggers an autophagic survival pathway in endothelial cells In this study, we aimed to investigate whether XBP1 splicing could also activate ...

Heart, BSCR Spring 2010 Meeting Abstracts, Andriana Margariti, Hongling Li, Daniel Martin, Anna Zampetaki, Yanhua Hu, Qingbo Xu, Lingfang Zeng

Date : 01/09/2010
Ehjcardiovascrec

MicroRNAs (miRNAs) are an emerging class of highly conserved, non-coding small RNAs that regulate gene expression on the post-transcriptional level by inhibiting the translation of protein from mRNA ...

Cardiovascular Research, REVIEWS: FOCUS ON MICRO RNA, Carmen Urbich, Angelika Kuehbacher, Stefanie Dimmeler

Date : 01/09/2008 Item size : 384605 bytes
Ehjcardiovascrec

Recent genome-wide studies of histone modifications confirmed that histone modifications control the chromatin state and gene transcription.1114 Histone methylation was thought to be a stable and ...

Cardiovascular Research, REVIEWS: FOCUS ON EPIGENETICS AND THE HISTONE CODE IN VASCULAR BIOLOGY, Kisho Ohtani, Stefanie Dimmeler

Date : 01/06/2011 Item size : 531732 bytes
Ehjcardiovascrec

Introduction Cardiac fibrosis is integral constituent of every form of chronic heart disease, and its relevance for disease progression is increasingly being recognized.1,2 However, no specific ...

Cardiovascular Research, Original Article, Xingbo Xu, Xiaoying Tan, Björn Tampe, Gunsmaa Nyamsuren, Xiaopeng Liu, Lars S. Maier, Samuel Sossalla, Raghu Kalluri, Michael Zeisberg, Gerd Hasenfuss, ...

Date : 01/03/2015 Item size : 319214 bytes
Ehjcardiovascrec

Epigentic marks are not in DNA sequence itself but on top of them, as chemical additions on DNA stretch (DNA methylation, Figure 2) or on those proteins in which the DNA is wrapped around ...

Cardiovascular Research, REVIEWS: FOCUS ON EPIGENETICS AND THE HISTONE CODE IN VASCULAR BIOLOGY, Mikko P. Turunen, Seppo Ylä-Herttuala

Date : 01/06/2011 Item size : 360857 bytes