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Decreased mitochondrial oxidative phosphorylation capacity in the human heart with left ventricular systolic dysfunction Introduction Heart failure (HF) is a clinical disease entity defined by ...

European Journal of Heart Failure, Stride, Nis, Larsen, Steen, Hey‐Mogensen, Martin, Sander, Kåre, Lund, Jens T., Gustafsson, Finn, Køber, Lars, Dela, Flemming

Date : 01/02/2013 Item size : 188249 bytes

Several studies suggest that such modulation of MMP activity can alter ventricular remodeling, myocardial dysfunction, and the progression of heart failure. KeywordsExtracellular matrixGene ...

Cardiovascular Research, Review, Yun You Li, Charles F. McTiernan, Arthur M. Feldman

Date : 01/05/2000 Item size : 466619 bytes

Introduction Heart failure (HF) remains a major cause of death worldwide.1 (Refer to Table 1 for all list of acronyms in the manuscript.) It is frequently preceded by cardiac hypertrophy defined ...

Cardiovascular Research, Cardiac biology and remodelling, Mirna N. Chahine, Maxime Mioulane, Markus B. Sikkel, Peter O'Gara, Cristobal G. Dos Remedios, Grant N. Pierce, Alexander R. Lyon, Gábor ...

Date : 01/01/2015 Item size : 336287 bytes

Abstract Aims Within the framework of studies aiming at regenerative medicine for cardiovascular disease, we have developed an in vitro model to analyse human embryonic stem (ES) cell engraftment ...

Cardiovascular Research, Original Article, Walter Habeler, Séverine Pouillot, Alexandra Plancheron, Michel Pucéat, Marc Peschanski, Christelle Monville

Date : 01/02/2009 Item size : 251860 bytes

KeywordsAldosteroneMineralo-receptorFibrosisHeartHypertensionTime for primary review 29 days. 1 Introduction Aldosterone (Aldo) plays an essential role in regulation of body sodium and potassium ...

Cardiovascular Research, Review, Claude Delcayre, Jean-Sébastien Silvestre

Date : 01/07/1999 Item size : 245502 bytes

Introduction Prolonged sympathetic nervous system activation with elevated circulating catecholamine levels have implications in human heart failure for both disease progression and survival.14 ...

Cardiovascular Research, Cardiac biology and remodelling, DaLiao Xiao, Chiranjib Dasgupta, Man Chen, Kangling Zhang, John Buchholz, Zhice Xu, Lubo Zhang

Date : 01/03/2014

Methods and results Using yeast two-hybrid assays with a human heart cDNA library, we identified atrial natriuretic peptide precursor A (NPPA), a well-known cardiac hypertrophy marker, as a novel ...

Cardiovascular Research, Original Article, Shokoufeh Mahmoodzadeh, Thi Hang Pham, Arne Kuehne, Britta Fielitz, Elke Dworatzek, Georgios Kararigas, George Petrov, Mercy M. Davidson, Vera ...

Date : 01/12/2012

Methods: We have carried out a comparative study of all KCNE subunits with KCNQ1 using the patch-clamp technique in mammalian cells. Results: While KCNQ1/KCNE1 heteromultimer reached high current ...

Cardiovascular Research, Original Article, Saïd Bendahhou, Céline Marionneau, Karinne Haurogne, Marie-Madeleine Larroque, Renaud Derand, Viktoria Szuts, Denis Escande, Sophie Demolombe, Jacques ...

Date : 15/08/2005

Different agents, such as calcium-antagonists, beta-adrenoceptor blockers, angiotensin converting enzyme inhibitors, metabolic interventions and antioxidants, have been reported to exert beneficial ...

Cardiovascular Research, Original Article, Naranjan S Dhalla, Xueliang Liu, Vincenzo Panagia, Nobuakira Takeda

Date : 01/11/1998

Methods: Subepicardial (epi), midmyocardial (mid), and subendocardial (endo) sections of the left ventricular free wall from end-stage failing (n=17) and nonfailing (n=5) human hearts were analyzed ...

Cardiovascular Research, Original Article, Jürgen Prestle, Sabine Dieterich, Michael Preuss, Ursula Bieligk, Gerd Hasenfuss

Date : 01/08/1999