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Ehjcardiovascrec

In this section, we review the current application of genetics in clinical management, focusing on hypertrophic cardiomyopathy as a paradigm; discuss state-of-the-art genetic testing technology; ...

Cardiovascular Research, INVITED SPOTLIGHT REVIEWS, Carolyn Y. Ho, Philippe Charron, Pascale Richard, Francesca Girolami, Karin Y. Van Spaendonck-Zwarts, Yigal Pinto

Date : 01/04/2015 Item size : 534020 bytes
Ehjcardiovascrec

Abstract Objective: Primary cardiac myocyte cultures are usually contaminated with variable parts of different cell types, such as fibroblasts, endothelial cells and smooth muscle cells. [...]the ...

Cardiovascular Research, Original Article, Claudius Diez, Andreas Simm

Date : 01/12/1998 Item size : 249350 bytes
Ehjcardiovascrec

The detailed understanding of the promoter regions essential for gene transcription and the different transcription factors, which are involved in promoter activation, is one of the scientific ...

Cardiovascular Research, Editorial, Markus Flesch

Date : 01/04/2001 Item size : 254094 bytes
Ehjcardiovascrec

Abstract Objective: Reactive oxygen species (ROS) such as superoxide have been linked to the hypertrophic response of the heart to stimuli including angiotensin II (AngII), mechanical stretch, and ...

Cardiovascular Research, Original Article, Adrienne Laskowski, Owen L. Woodman, Anh H. Cao, Grant R. Drummond, Tanneale Marshall, David M. Kaye, Rebecca H. Ritchie

Date : 01/10/2006 Item size : 316495 bytes
Ehjcardiovascrec

Abstract Objective: Tumor necrosis factor α (TNFα) is thought to play a key role in the pathogenesis of cardiac failure. Protein binding to the E-box enhancer element in the αMHC promoter ...

Cardiovascular Research, Original Article, Denise Hilfiker-Kleiner, Andres Hilfiker, Bernhard Schieffer, David Engel, Douglas L Mann, Kai C Wollert, Helmut Drexler

Date : 01/02/2002 Item size : 272970 bytes
Ehjcardiovascrec

Regenerated cardiomyocytes are important candidates for cell transplantation, but as they are stem cell derived, they can be contaminated with various cell types, thereby requiring characterization ...

Cardiovascular Research, Research Article, Naoichiro Hattan, Haruko Kawaguchi, Kiyoshi Ando, Eriko Kuwabara, Jun Fujita, Mitsushige Murata, Makoto Suematsu, Hidezo Mori, Keiichi Fukuda

Date : 01/02/2005
Ehjcardiovascrec

Cardioprotection by long-term ETA receptor blockade and ACE inhibition in rats with congestive heart failure: mono- versus combination therapy Abstract Objectives: We investigated the effects of ...

Cardiovascular Research, Original Article, Daniela Fraccarollo, Johann Bauersachs, Markus Kellner, Paolo Galuppo, Georg Ertl

Date : 01/04/2002
Ehjcardiovascrec

Methods and results We have found that endothelium-specific RTEF-1 transgenic mice (VE-Cad/RTEF-1) developed significant cardiac hypertrophy after transverse aortic constriction surgery, as evidenced ...

Cardiovascular Research, Original Article, Ming Xu, Yi Jin, Qinhui Song, Jiaping Wu, Melissa J. Philbrick, Brittany L. Cully, Xiaojin An, Lin Guo, Feng Gao, Jian Li

Date : 01/05/2011
Ehjcardiovascrec

Introduction Small molecule inhibitors that occupy the ATP binding sites of receptor tyrosine kinases (RTKs) have been successful in inhibiting the abnormally high kinase activity and uncontrolled ...

Cardiovascular Research, Cardiac biology and remodelling, Pamela Ann Harvey, Leslie Anne Leinwand

Date : 01/07/2015
Ehjcardiovascrec

KeywordsStem cellsMyocytesMitochondriaEndothelial receptorsIschemiaTime for primary review 27 days. 1 Basic studies 1.1 Cardiomyocyte differentiation of embryonic stem cells Embryonic stem cells (ES) ...

Cardiovascular Research, Review, Michael J. Goldenthal, José Marín-García

Date : 01/05/2003