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In order to investigate the existence of potential gender differences on the effects of intrauterine undernutrition, both male and female offspring of pregnant Wistar rats on normal and restricted ...

Cardiovascular Research, Original Article, Maria do Carmo P Franco, Robéria Maria M.P Arruda, Ana Paula Villela Dantas, Elisa Mitiko Kawamoto, Zuleica B Fortes, Cristoforo Scavone, Maria Helena C ...

Date : 01/10/2002 Item size : 250179 bytes

[...]lysine acetyl transferase (KAT) activity associated with Nup153 was higher in mdx hearts paralleling increased binding with the lysine acetylases P300/CBP-associated factor (PCAF) and ...

Cardiovascular Research, Original Article, Simona Nanni, Agnese Re, Cristian Ripoli, Aoife Gowran, Patrizia Nigro, Domenico D’Amario, Antonio Amodeo, Filippo Crea, Claudio Grassi, Alfredo ...

Date : 01/11/2016 Item size : 368731 bytes

Diminished NO levels have been, in fact, associated with atherosclerosis, cardiac infarction, and diabetes, to cite some the most common occurrences.4,5 In mice knock-out for NO synthases, several ...

Cardiovascular Research, REVIEWS: FOCUS ON EPIGENETICS AND THE HISTONE CODE IN VASCULAR BIOLOGY, Barbara Illi, Claudia Colussi, Jessica Rosati, Francesco Spallotta, Simona Nanni, Antonella Farsetti, ...

Date : 01/06/2011 Item size : 585803 bytes

Abstract Background: Plasma low density lipoproteins (LDL) play a key role in the pathogenesis of atherosclerosis. Methods: Expression levels of C-4 sterol methyl oxidase gene (ERG25), sterol ...

Cardiovascular Research, Original Article, C. Rodriguez, B. Raposo, J. Martínez-González, V. Llorente-Cortés, G. Vilahur, L. Badimon

Date : 01/04/2003 Item size : 279838 bytes

Atherosclerosis is epidemiologically linked and causally related to the presence of risk factors Despite their diversity, major risk factors for cardiovascular disease such as hypercholesterolaemia, ...

Cardiovascular Research, Editorial, Raffaele De Caterina, Rosalinda Madonna

Date : 01/03/2009 Item size : 231905 bytes

Abstract Objective: Tumor necrosis factor α (TNFα) is thought to play a key role in the pathogenesis of cardiac failure. Protein binding to the E-box enhancer element in the αMHC promoter ...

Cardiovascular Research, Original Article, Denise Hilfiker-Kleiner, Andres Hilfiker, Bernhard Schieffer, David Engel, Douglas L Mann, Kai C Wollert, Helmut Drexler

Date : 01/02/2002 Item size : 272970 bytes

Abstract Objectives Septic shock and sequential multiple organ failure remain the cause of death in septic patients. Synthetic small interfering RNAs (siRNAs) specifically suppress gene expression ...

Cardiovascular Research, Original Article, Naoyuki Matsuda, Yasuo Takano, Shun-ichiro Kageyama, Noboru Hatakeyama, Kiyoshi Shakunaga, Isao Kitajima, Mitsuaki Yamazaki, Yuichi Hattori

Date : 01/10/2007 Item size : 307264 bytes

Abstract The endothelium plays a key role in the maintenance of vascular homeostasis, and increased oxidative stress in vascular disease leads to reduced nitric oxide bioavailability and impaired ...

Cardiovascular Research, Review, Giovanni E. Mann, David J. Rowlands, Francois Y.L. Li, Patricia de Winter, Richard C.M. Siow

Date : 15/07/2007 Item size : 768335 bytes

Abstract Markers of increased oxidative stress are known to be elevated following acute myocardial infarction and in the context of chronic left ventricular hypertrophy or heart failure, and their ...

Cardiovascular Research, Review, Colin E. Murdoch, Min Zhang, Alison C. Cave, Ajay M. Shah

Date : 15/07/2006

Two principal isozymes of heme oxygenase have been identified, a constitutive isoform HO-2 (Mr34000) and an inducible isoform HO-1 (Mr32000), which is expressed at a low basal level in vascular ...

Cardiovascular Research, Review, Richard C.M. Siow, Hideyo Sato, Giovanni E. Mann

Date : 01/02/1999