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The development and structure of blood vessels are highly adapted to haemodynamic forces, such as shear stress, cyclic stretch, and circumferential wall stress, generated by the conductance of ...

Cardiovascular Research, SPOTLIGHT REVIEWS: SPOTLIGHT ON BIOMECHANICAL FACTORS IN CARDIOVASCULAR DISEASE, Peter Neth, Maliheh Nazari-Jahantigh, Andreas Schober, Christian Weber

Date : 15/07/2013 Item size : 558042 bytes

Methods: Shear stress and statin effects in combination with TNF-α were determined in human umbilical vein endothelial cells by quantitative measurements of the steady-state levels and stability ...

Cardiovascular Research, Original Article, Johannes V. van Thienen, Joost O. Fledderus, Rob J. Dekker, Jakub Rohlena, Gerben A. van IJzendoorn, Neeltje A. Kootstra, Hans Pannekoek, Anton J.G. ...

Date : 01/11/2006 Item size : 296044 bytes

Stearoyl-CoA desaturase-1 (SCD1), which catalyzes the biosynthesis of monounsaturated fatty acids, affects the lipid composition and fluidity of the cell membrane. [...]we examined the effect of ...

Cardiovascular Research, Original Article, Xiaomei Qin, Jianwei Tian, Peng Zhang, Yanbo Fan, Li Chen, Youfei Guan, Yi Fu, Yi Zhu, Shu Chien, Nanping Wang

Date : 01/06/2007 Item size : 298015 bytes

The review article from Frueh et al.8 embraces this complexity and describes the current challenges of large data sets and the application of systems biology in the exploration of the effects of ...

Cardiovascular Research, Editorial, Paul C. Evans, Brenda R. Kwak

Date : 15/07/2013 Item size : 192536 bytes

Atherosclerosis is epidemiologically linked and causally related to the presence of risk factors Despite their diversity, major risk factors for cardiovascular disease such as hypercholesterolaemia, ...

Cardiovascular Research, Editorial, Raffaele De Caterina, Rosalinda Madonna

Date : 01/03/2009 Item size : 231905 bytes

Reactive oxygen species (ROS) such as superoxide and H2O2 function as signaling molecules in many aspects of growth factor-mediated responses including angiogenesis. Vascular endothelial growth ...

Cardiovascular Research, Review, Masuko Ushio-Fukai

Date : 15/07/2006 Item size : 528604 bytes

Introduction Atherosclerosis is typically localized to the carotid artery sinus, the coronary arteries, the abdominal aorta, and the superficial femoral arteries.1 These are regions of complex blood ...

Cardiovascular Research, Original Article, Daniel E. Conway, Yumiko Sakurai, Daiana Weiss, J. David Vega, W. Robert Taylor, Hanjoong Jo, Suzanne G. Eskin, Craig B. Marcus, Larry V. McIntire

Date : 01/03/2009

Abstract Objective: The antiapoptotic effect of p21Waf1/Cip1/Sdi1 (p21) was examined in human umbilical vein endothelial cells (HUVEC) exposed to laminar shear stress (SS) or to the nitric oxide ...

Cardiovascular Research, Original Article, Stefania Mattiussi, Paolo Turrini, Lucia Testolin, Fabio Martelli, Germana Zaccagnini, Antonella Mangoni, Laura M Barlucchi, Annalisa Antonini, Barbara ...

Date : 01/03/2004

[...]using a rat vein in vivo arterialization model, early (114 days) CRP3/MLP immunostaining was observed predominantly in the inner layer and later (2890 days) it appeared more scattered in the ...

Cardiovascular Research, Original Article, Luciene Cristina Gastalho Campos, Ayumi Aurea Miyakawa, Valerio Garrone Barauna, Leandro Cardoso, Thaiz Ferraz Borin, Luis Alberto de Oliveira Dallan, Jose ...

Date : 01/07/2009

Abstract Objective: We previously showed that mitochondrial coupling factor 6 (CF6), an endogenous inhibitor of prostacyclin synthesis and a vasoconstrictor, is present on the surface of human ...

Cardiovascular Research, Original Article, Hirofumi Tomita, Tomohiro Osanai, Tsutomu Toki, Satoko Sasaki, Naotaka Maeda, Reiichi Murakami, Koji Magota, Minoru Yasujima, Ken Okumura

Date : 01/07/2005