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Insulin-like growth factor-1 mediates stretch-induced upregulation of myostatin expression in neonatal rat cardiomyocytes Addition of the p38 mitogen-activated protein (MAP) kinase inhibitor ...

Cardiovascular Research, Original Article, Kou-Gi Shyu, Wei-Hsu Ko, Wei-Shiung Yang, Bao-Wei Wang, Peiliang Kuan

Date : 01/12/2005 Item size : 269233 bytes

[...]we focus on the development and use of miRNA antagonists (antagomirs) to target miRNAs in vivo, which may translate into novel therapeutic strategies for heart disease in the ...

Cardiovascular Research, REVIEWS: FOCUS ON MICRO RNA, Thomas Thum, Daniele Catalucci, Johann Bauersachs

Date : 01/09/2008 Item size : 417406 bytes

RNA-binding proteins affect the proteome of a single cell by controlling alternative splicing, transport, localization, and stability of their target RNAs.1 They often display tissue-specific ...

Cardiovascular Research, Editorial, Elisabeth Ehler

Date : 01/06/2012 Item size : 172852 bytes

3.1 Identification of Rbm24 as a cardiac-enriched gene Transcriptome analysis on hESC-derived cardiomyocytes identified a large number of genes with little or no information, including RBM24 with ...

Cardiovascular Research, Original Article, Kar Lai Poon, Kar Tong Tan, Yang Ye Wei, Chee Peng Ng, Alan Colman, Vladimir Korzh, Xiu Qin Xu

Date : 01/06/2012 Item size : 328238 bytes

Beneficial effects of endurance training on cardiac and skeletal muscle energy metabolism in heart failure Abstract As endurance training improves symptoms and quality of life and decreases ...

Cardiovascular Research, Review, Renée Ventura-Clapier, Bertrand Mettauer, Xavier Bigard

Date : 01/01/2007 Item size : 517400 bytes

In order to gain a better understanding of general aspects of aging and to identify aging biomarkers, we are currently using DNA microarray analysis to study caloric restriction (CR) as a model ...

Cardiovascular Research, Review, Sang-Kyu Park, Tomas A. Prolla

Date : 01/05/2005

Methods and results The primary effect of exogenous expression of RIP140 mRNA (real-time PCR) and protein (western blotting) in transgenic mice is impaired postnatal heart function. RIP140 exogenous ...

Cardiovascular Research, Original Article, Asmaà Fritah, Jennifer H. Steel, Donna Nichol, Nadeene Parker, Sharron Williams, Anthony Price, Leena Strauss, Timothy A. Ryder, Margaret A. Mobberley, ...

Date : 01/06/2010

Mice lacking the muscle LIM protein (MLP) develop morphological and clinical signs resembling human dilated cardiomyopathy and heart failure. Light and electron microscopy revealed a disorganization ...

Cardiovascular Research, Research Article, Bianca J.C. van den Bosch, Caroline M.M. van den Burg, Kees Schoonderwoerd, Patrick J. Lindsey, Hans R. Scholte, René F.M. de Coo, Eva van Rooij, Howard ...

Date : 01/02/2005

Abstract Objective: We examined the functional consequences of expressing adult rabbit fast skeletal sarcoplasmic reticulum (SR) Ca2+-ATPase (SERCA1a) in isolated adult rat ventricular ...

Cardiovascular Research, Original Article, Nathalie Chossat, Frank Griscelli, Philippe Jourdon, Damien Logeart, Thierry Ragot, Michèle Heimburger, Michel Perricaudet, Anne-Marie Lompré, ...

Date : 01/02/2001

KeywordsCalcium (cellular)Genetic codeHeart failureSR (function)Ventricular function 1 Introduction The mammalian organism responds to chronic pressure and volume overload of the heart with a ...

Cardiovascular Research, Update review, U Ravens, D Dobrev

Date : 01/01/2000