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Rationale Phospholipase A2, group 7 (PLA2g7), the plasma isoform of a platelet-activating factor acetylhydrolases, also known as lipoprotein associated phospholipase A2, is a circulating enzyme that ...

Heart, BAS/BSCR Poster Abstracts, Q Xiao, A Pepe, G Wang, Z Luo, L Zeng, S Ye, Q Xu

Date : 15/10/2011

In the present study, we therefore searched for adenosine-induced changes in the expression of early genes in cultured human coronary artery smooth muscle cells (HCASMCs). Methods and results ...

Cardiovascular Research, Original Article, Peter Mayer, Annette Viktoria Hinze, Anja Harst, Ivar von Kügelgen

Date : 01/04/2011 Item size : 339812 bytes

Abstract Objective: Primary cardiac myocyte cultures are usually contaminated with variable parts of different cell types, such as fibroblasts, endothelial cells and smooth muscle cells. [...]the ...

Cardiovascular Research, Original Article, Claudius Diez, Andreas Simm

Date : 01/12/1998 Item size : 249350 bytes

Two principal isozymes of heme oxygenase have been identified, a constitutive isoform HO-2 (Mr34000) and an inducible isoform HO-1 (Mr32000), which is expressed at a low basal level in vascular ...

Cardiovascular Research, Review, Richard C.M. Siow, Hideyo Sato, Giovanni E. Mann

Date : 01/02/1999

Introduction Endothelin-1 (ET-1) plays an important role in various cardiovascular diseases such as coronary artery disease (CAD), pulmonary hypertension (PH), and high-altitude disease14 through its ...

Cardiovascular Research, ORIGINAL ARTICLES: SPOTLIGHT ON SMOOTH MUSCLE CELLS AND VASCULAR DISEASES, Tetsuya Hisada, Makoto Ayaori, Nobuhiro Ohrui, Hiroshi Nakashima, Kazuhiro Nakaya, Harumi ...

Date : 15/07/2012

Downregulation of SMA by LPS is not a result of altered signaling of ET1 or TGF-β receptors, and it is not mediated by canonical (for LPS) mechanisms, such as production of prostaglandins or ...

Cardiovascular Research, Original Article, Nathan Sandbo, Sebastien Taurin, Douglas M. Yau, Steven Kregel, Richard Mitchell, Nickolai O. Dulin

Date : 01/05/2007

Abstract Aims Human cytomegalovirus (HCMV) infection has been linked to the pathogenesis of vasculopathies; however, its pathogenic relevance remains to be established. [...]HCMV infection ...

Cardiovascular Research, Vascular biology, Barbara Reinhardt, Rinesh Godfrey, Guido Fellbrich, Hedwig Frank, Anke Lüske, Servé Olieslagers, Thomas Mertens, Johannes Waltenberger

Date : 01/11/2014

Introduction Vascular smooth muscle cells (VSMCs) can undergo profound and reversible changes in phenotype in response to environmental changes.1 In particular, the switch to the so called ...

Cardiovascular Research, Original Article, Claudio Iaconetti, Salvatore De Rosa, Alberto Polimeni, Sabato Sorrentino, Clarice Gareri, Annarita Carino, Jolanda Sabatino, Maria Colangelo, Antonio ...

Date : 01/09/2015

Introduction The discovery that bone marrow-derived endothelial progenitor cells (EPC) can be mobilized into the circulatory system after endothelial injury and contribute to damaged vessel repair ...

Cardiovascular Research, Original Article, Marta Díez, Melina M. Musri, Elisabet Ferrer, Joan A. Barberà, Víctor I. Peinado

Date : 01/12/2010

Abstract Objective: Aberrant regulation of the synthesis and degradation of the extracellular matrix (ECM) is associated with the pathophysiology of vascular disease. Methods: Cultures of the rabbit ...

Cardiovascular Research, Original Article, Atai Watanabe, Masahiko Kurabayashi, Masashi Arai, Kenichi Sekiguchi, Ryozo Nagai

Date : 01/07/2001