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Among 25 relatives without evidence of asymmetric septal hypertrophy, two over 20 years and 10 under 20 years of age showed increased voltage of QRS anterior forces (Qz amplitude greater than 0.80 ...

British Heart Journal, Research Article, F Loperfido, R Fiorilli, A Digaetano, M Di Gennaro, P Santarelli, F Bellocci, E Coppola, P Zecchi

Date : 01/06/1982

A Varnava, C Baboonian, F Davison, L de Cruz, P M Elliott, M J Davies, W J McKenna Department of Cardiological Sciences, St George's Hospital Medical School, Cranmer Terrace, London SW17 ORE, UK Dr ...

Heart, Paper, A Varnava, C Baboonian, F Davison, L de Cruz, P M Elliott, M J Davies, W J McKenna

Date : 01/11/1999

Introduction Familial hypertrophic cardiomyopathy (FHC) is a relatively common autosomal dominant genetic disease characterized by ventricular hypertrophy, myofibrillar disarray, often clinically ...

Cardiovascular Research, Original Article, Theodore P. Abraham, Michelle Jones, Katarzyna Kazmierczak, Hsin-Yueh Liang, Aurelio C. Pinheiro, Cory S. Wagg, Gary D. Lopaschuk, Danuta Szczesna-Cordary

Date : 01/04/2009 Item size : 284513 bytes

Introduction Familial hypertrophic cardiomyopathy (HCM) is a primary disorder of cardiac muscle, and is associated with thickened ventricular wall and ventricular septum, increased myocardial ...

Cardiovascular Research, Cardiac biology and remodelling, Lu Han, Yang Li, Jason Tchao, Aaron D. Kaplan, Bo Lin, You Li, Jocelyn Mich-Basso, Agnieszka Lis, Narmeen Hassan, Barry London, Glenna C.L. ...

Date : 01/11/2014

Hypertrophied cells, already manifesting marked potassium channel abnormalities, are highly sensitive to metabolic conditions such as hypokalemia, or QT prolonging drugs that further prolong ...

Cardiovascular Research, Original Article, Peter R. Kowey, Gan-Xin Yan, Xiaoping Xu

Date : 01/08/2000

Aims It is not known whether the apparent normality of echocardiographic examination results, in subjects bearing a mutation for hypertrophic cardiomyopathy but without ultrasonic left ventricular ...

European Heart Journal, Hagège, A.A., Dubourg, O., Desnos, M., Mirochnik, R., Isnard, G., Bonne, G., Carrier, L., Guicheney, P., Bouhour, J-B., Schwartz, K., Komajda, M.

Date : 01/03/1998

Introduction Hypertrophic cardiomyopathy is defined by the presence of increased ventricular wall thickness or mass in the absence of loading conditions (hypertension, valve disease) sufficient to ...

European Heart Journal, Friedrich, Felix W., Bausero, Pedro, Sun, Yuli, Treszl, Andras, Krämer, Elisabeth, Juhr, Denise, Richard, Pascale, Wegscheider, Karl, Schwartz, Ketty, Brito, Dulce, ...

Date : 01/07/2009 Item size : 323515 bytes

Abstract Aims To study the diagnostic value of a new 2D left ventricle hypertrophy (2D LVH) score in families with hypertrophic cardiomyopathy (HCM) in comparison with the conventional maximal wall ...

European Heart Journal, Forissier, Jean F., Charron, Philippe, du Montcel, Sophie Tezenas, Hagège, Albert, Isnard, Richard, Carrier, Lucie, Richard, Pascale, Desnos, Michel, Bouhour, Jean B., ...

Date : 01/09/2005 Item size : 166153 bytes

The subset of HCM patients with familial hypertrophic cardiomyopathy (FHC) displays a highly variable phenotype ranging from no symptoms to overt cardiomyopathy with early onset sudden cardiac ...

Cardiovascular Research, Ingwall, Joanne S.

Date : 15/07/2014 Item size : 108278 bytes

In addition clinical investigations of relatives at risk of having inherited the disease and genetic analysis to identify disease-causing mutations in affected families were seldom initiated. The ...

European Heart Journal, Mogensen, Jens, Bahl, Ajay, McKenna, William J

Date : 01/03/2003 Item size : 96769 bytes