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Methods: Ca2+-dependent and Ca2+-independent NOS activities (pmol min1 mg1 protein), NOS protein expression (quantitative immunoblot), cGMP content (pmol mg1 protein) and LV work (Joules) were ...

Cardiovascular Research, Original Article, Heather Fraser, Sandra T. Davidge, Alexander S. Clanachan

Date : 01/04/2000 Item size : 303680 bytes

Reduced stimulation of endothelial NO synthase (NOS) by growth hormone and/or insulin-like growth factor-I (IGF-I) may be one of the mechanisms contributing to reduced NO elaboration in chronic heart ...

Cardiovascular Research, Original Article, Karl Josef Osterziel, Stefanie M Bode-Böger, Oliver Strohm, Annette E Ellmer, Nana Bit-Avragim, Dankward Hänlein, Michael B Ranke, Rainer Dietz, ...

Date : 14/01/2000 Item size : 268198 bytes

Anaesthesia was induced after pre-medication with ketamine [10 mg/kg intramuscular (IM)] and xylazine (0.2 mg/kg IM) and with 5% isoflurane using a face mask. The experimental protocol was approved ...

Europace, BASIC SCIENCE, Ilse Lenaerts, Patricia Holemans, Peter Pokreisz, Karin R. Sipido, Stefan Janssens, Hein Heidbüchel, Rik Willems

Date : 01/05/2011

To investigate whether calcium antagonists or angiotensin-converting enzyme (ACE) inhibitors increase vascular nitric oxide activity, we assessed systemic and renal vascular sensitivity to nitric ...

Cardiovascular Research, Original Article, Lioe-Ting Dijkhorst-Oei, Jaap J. Beutler, Erik S.G. Stroes, Hein A. Koomans, Ton J. Rabelink

Date : 01/11/1998

[...]the contribution of NO to the regulation of vasomotor tone in the coronary resistance vessels is more apparent in the human heart, both at rest [57] and during metabolic stimulation via atrial ...

Cardiovascular Research, Original Article, Dirk J. Duncker, René Stubenitsky, Pim A.L. Tonino, Pieter D. Verdouw

Date : 01/09/2000

Increased counteracting effect of eNOS and nNOS on an α1-adrenergic rise in total peripheral vascular resistance in spontaneous hypertensive rats Abstract Objective: The hypertension in ...

Cardiovascular Research, Original Article, Torill Berg

Date : 01/09/2005

Abstract Severe sepsis and septic shock, which are among the most common causes of death in intensive care units worldwide, cause high morbidity, mortality, and social and economic ...

Cardiovascular Research, REVIEWS: FOCUS ON INORGANIC NITRITE AND NITRATE, Anje Cauwels, Peter Brouckaert

Date : 15/02/2011

In rats treated for 36 h, vascular cyclic AMP levels were enhanced in the aorta and inhibition of protein kinase A attenuated EDHF-mediated relaxations of the renal artery without affecting responses ...

Cardiovascular Research, Original Article, E. Büssemaker, R. Popp, B. Fisslthaler, C.M. Larson, I. Fleming, R. Busse, R.P. Brandes

Date : 01/07/2003

Methods: To test this hypothesis, we examined effects of cholinergic blockade on blood pressure, heart rate and peripheral vascular responses to systemic infusion of the nitric-oxide-dependent ...

Cardiovascular Research, Original Article, Mattia Lepori, Claudio Sartori, Hervé Duplain, Pascal Nicod, Urs Scherrer

Date : 01/09/2001

Impaired skin blood flow response to environmental heating in chronic heart failure Abstract Aims We examined the thermoregulatory response to heat exposure in patients with chronic heart ...

European Heart Journal, Green, Daniel J., Maiorana, Andrew J., Siong, Jeffrey Ha Jin, Burke, Valerie, Erickson, Matthew, Minson, Christopher T., Bilsborough, William, O'Driscoll, Gerry

Date : 01/02/2006