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There was no increase in apoptosis detected in eNOS transduced cells after 24 or 72 h. Conclusion: eNOS gene transfer to vascular SMCs inhibits cell proliferation via upregulation of p27 and p21 ...

Cardiovascular Research, Sato, Jun’ichi, Nair, Kamala, Hiddinga, Jay, Eberhardt, Norman L., Fitzpatrick, Lorraine A., Katusic, Zvonimir S., O’Brien, Timothy

Date : 01/09/2000 Item size : 294003 bytes

[...]increase in vessel wall thickness and hyperplasia were shown to occur following ligation of the carotid artery in NO synthase (eNOS) knockout mice suggesting NO to be a negative regulator of ...

Cardiovascular Research, Holt, Cathy M.

Date : 01/09/2000 Item size : 141301 bytes

[...]TSP1 was initially studied in relation to coagulation, growth factor signaling and angiogenesis. The term matricellular protein has been employed for over 20years and was coined to embrace the ...

Cardiovascular Research, Rogers, Natasha M., Ghimire, Kedar, Calzada, Maria J., Isenberg, Jeffrey S.

Date : 01/07/2017 Item size : 609419 bytes

Effects of nebivolol on proliferation and apoptosis of human coronary artery smooth muscle and endothelial cells The aim of this study was to investigate the effects of the new β-blocker ...

Cardiovascular Research, Brehm, B.R, Wolf, S.C, Bertsch, D, Klaussner, M, Wesselborg, S, Schüler, S, Schulze-Osthoff, K

Date : 01/02/2001

Abstract Aims The presence and potential function of transient receptor potential melastatin 7 (TRPM7), a Ca2+-permeable non-selective cation channel of the TRP channel superfamily in human vascular ...

Cardiovascular Research, Inoue, Koichi, Xiong, Zhi-Gang

Date : 01/08/2009 Item size : 345143 bytes

Following arterial injury, NO has been shown to serve many vasoprotective roles, including inhibition of platelet aggregation and adherence to the site of injury, inhibition of leukocyte adherence, ...

Cardiovascular Research, Kibbe, Melina, Billiar, Timothy, Tzeng, Edith

Date : 15/08/1999 Item size : 343216 bytes

Estrogen receptor-α gene transfer into bovine aortic endothelial cells induces eNOS gene expression and inhibits cell migration Abstract Objectives: It has been suggested that estrogen may ...

Cardiovascular Research, Tan, Enqing, Gurjar, Milind V, Sharma, Ram V, Bhalla, Ramesh C

Date : 15/08/1999 Item size : 323973 bytes

Abstract Aims We have investigated the effects of magnesium lithospermate B (MLB), the active compound of the Oriental herbal remedy, Salvia miltiorrhizae, on endothelial dysfunction associated with ...

Cardiovascular Research, Kim, So Hun, Kim, Soo Hyun, Choi, Minah, Lee, Yongho, Kim, Young Ook, Ahn, Duck Sun, Kim, Young Ho, Kang, Eun Seok, Lee, Eun Jig, Jung, Mankil, Cho, Jin Won, Williams, Darren ...

Date : 01/09/2010 Item size : 318631 bytes

Proposed mechanisms for the arrhythmogenic effects of ET-1 are prolongation or increased dispersion of monophasic action potential duration, QT prolongation, development of early ...

Cardiovascular Research, Duru, Fırat, Barton, Matthias, Lüscher, Thomas F., Candinas, Reto

Date : 01/02/2001

Abstract Aims Anti-platelet agents, such as dipyridamole, have several clinical benefits for peripheral artery disease with the speculation of angiogenic potential that could preserve ischaemic ...

Cardiovascular Research, Venkatesh, Prasanna K., Pattillo, Christopher B., Branch, Billy, Hood, Jay, Thoma, Steven, Illum, Sandra, Pardue, Sibile, Teng, Xinjun, Patel, Rakesh P., Kevil, Christopher G.

Date : 01/03/2010 Item size : 322406 bytes