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Obesity and excessive weight put a strain on the entire circulatory system.1 Obese individuals are also more likely to have high cholesterol, high blood pressure, and diabetesall of which may further ...

European Heart Journal, Editorial, Francesco Paneni, Sarah Costantino, Francesco Cosentino

Date : 15/11/2014 Item size : 186028 bytes

The cardiac endothelium in cardiovascular homeostasis In the pathophysiology of HF, a pivotal role has been attributed to generalized endothelial dysfunction, in particular in the cardiac, pulmonary, ...

European Heart Journal, Clinical update, Shir Lynn Lim, Carolyn S.P. Lam, Vincent F.M. Segers, Dirk L. Brutsaert, Gilles W. De Keulenaer

Date : 14/08/2015 Item size : 707313 bytes

[...]AT2 receptor stimulation inhibits growth and promotes apoptosis, an important mechanism during development and tissue remodeling. [...]ANG stimulates the release of nitric oxide (NO)/cGMP via ...

Cardiovascular Research, Review, Olaf Jöhren, Andreas Dendorfer, Peter Dominiak

Date : 01/06/2004 Item size : 423872 bytes

Abstract Proliferation of mesangial cells and expansion of mesangial matrix is a hallmark of glomerular disease leading to end-stage renal failure and requiring renal replacement ...

Cardiovascular Research, Review, Lutz Buschhausen, Stefan Seibold, Oliver Gross, Tilman Matthaeus, Manfred Weber, Eckhard Schulze-Lohoff

Date : 15/08/2001 Item size : 366251 bytes

Nitric oxide (NO) influences many aspects of cardiac function including excitationcontraction coupling, myofilament function, oxygen consumption, substrate metabolism, and cell growth and survival ...

Cardiovascular Research, Editorial, Ajay M. Shah

Date : 01/06/2005 Item size : 156913 bytes

Clinically, chronic systolic LV overload most commonly results from myocardial infarction (MI), or chronic pressure overload, including hypertension and aortic stenosis.1 Despite the apparent ...

Cardiovascular Research, Editorial, Dirk J. Duncker, Elza D. van Deel

Date : 01/03/2012 Item size : 179893 bytes

Animal as well as human studies have shown beneficial changes in biological phenomena related to cardiovascular health after the consumption of polyphenol-rich foods such as cocoa, red wine, tea, and ...

Cardiovascular Research, Editorial, José A. Páramo

Date : 01/07/2008 Item size : 165875 bytes

[...]the recent report by Babaei and Stewart [1] is in keeping with previous observations. More importantly, we have finally demonstrated that the conditioned media from SMC transfected with eNOS or ...

Cardiovascular Research, Letter to the Editor, Józef Dulak, Alicja Józkowicz

Date : 01/12/2002 Item size : 147610 bytes

Chronic cardiotoxicity, which ranges from an incidence of 1% at a cumulative dose of 550 mg/m2 to >30% at cumulative doses above 5601160 mg/m2, can occur at any time after initiation of treatment and ...

Cardiovascular Research, Editorial, Charles F. McTiernan

Date : 01/02/2011 Item size : 177302 bytes

High-density lipoproteins (HDLs) have captured the imagination of scientists and physicians from virtually the time they were originally described, but especially after the cholesterol carried in HDL ...

Cardiovascular Research, Editorial, Daniel J. Rader

Date : 01/08/2014 Item size : 380769 bytes