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Methods/results: In isolated, constant pressure (CP) perfused guinea pig hearts a step change of arterial pCO2 from 38.6 to 61.4 mm Hg induced a bi-phasic flow response with an early transient ...

Cardiovascular Research, Original Article, Anke Heintz, Thea Koch, Andreas Deussen

Date : 01/04/2005 Item size : 258820 bytes

Abstract Nitric oxide (NO) generated constitutively within the heart has long been known to influence myocardial function; however, the precise nature of these effects has been controversial at least ...

Cardiovascular Research, Review, Mike Seddon, Ajay M. Shah, Barbara Casadei

Date : 15/07/2007 Item size : 427884 bytes

Abstract Objective: The aims were to validate the use of a direct reading NO electrode, to compare the effects of diverse acting drugs on altering coronary flow (CF) and NO release, and to examine ...

Cardiovascular Research, Original Article, Satoshi Fujita, David L Roerig, Zeljko J Bosnjak, David F Stowe

Date : 01/06/1998 Item size : 291609 bytes

Adalet Gürlek1, Kerim Esenboða3, Özgür Ulaþ Özcan1, Ömer Faruk Çiçek4, Pelin Arýbal Ayral2, Güzin Özelçi Kavas2, Çetin Erol1 1Departments of Cardiology, ...

Date : 13/01/2017 Item size : 36933 bytes

Abstract Objectives: ATP-sensitive potassium channels (K+ATP) prominently contribute to basal coronary tone; however, flow reserve during exercise remains unchanged despite channel blockade with ...

Cardiovascular Research, Original Article, Pasquale Pagliaro, Nazareno Paolocci, Takayoshi Isoda, Walter F Saavedra, Genshiro Sunagawa, David A Kass

Date : 01/03/2000

Among the physiological mechanisms that are known to influence autoregulation are metabolic factors (i.e., oxygen tension and/or tissue metabolites) and the so-called myogenic response which mediates ...

Cardiovascular Research, Original Article, Jurgen A.M Avontuur, Hajo A Bruining, Can Ince

Date : 01/08/1997

Conclusions In native non-critical coronary artery disease or following PCI, coronary microvascular endothelial function is not improved by co-administration of Ach and BH4. Once viewed largely as a ...

Cardiovascular Research, Original Article, Matthew I. Worthley, Ronak S. Kanani, Yi-Hui Sun, Yichun Sun, David M. Goodhart, Michael J. Curtis, Todd J. Anderson

Date : 01/12/2007

Cardiac uptake of free fatty acids decreased by 43% after 1 h (P<0.05) and returned to control values at 2 h. Cardiac respiratory quotient increased from 0.76±0.03 to 1.05±0.07, indicating a ...

Cardiovascular Research, Original Article, Fabio A. Recchia, Patrick I. McConnell, Kit E. Loke, Xiaobin Xu, Manuel Ochoa, Thomas H. Hintze

Date : 01/11/1999

Abstract Aims This study addressed the hypotheses that the hypercapnic flow response in wild-type (WT) mouse heart is mainly mediated by nitric oxide (NO) and, thus, severely blunted in endothelial ...

Cardiovascular Research, Original Article, Anke Heintz, Martin Damm, Markus Brand, Thea Koch, Andreas Deussen

Date : 01/01/2008

Abstract Aims Cardiovascular disease and type 2 diabetes mellitus are associated with low plasma concentration of adiponectin. Haemodynamics, infarct size, and expression of endothelial NO-synthase ...

Cardiovascular Research, Original Article, Adrian T. Gonon, Ulrika Widegren, Aliaksandr Bulhak, Firoozeh Salehzadeh, Jonas Persson, Per-Ove Sjöquist, John Pernow

Date : 01/04/2008