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Ehjcardiovascrec

Abstract Objective: We have shown previously that there is a relative nitric oxide deficiency at the level of vascular endothelium in the stroke-prone spontaneously hypertensive rat (SHRSP), a model ...

Cardiovascular Research, Original Article, M.Yvonne Alexander, M.Julia Brosnan, Carlene A Hamilton, Paul Downie, Alison M Devlin, Fiona Dowell, William Martin, Howard M Prentice, Timothy ...

Date : 15/08/1999 Item size : 290659 bytes
Ehjcardiovascrec

GTP cyclohydrolase I gene transfer augments intracellular tetrahydrobiopterin in human endothelial cells: effects on nitric oxide synthase activity, protein levels and dimerisation Results: GTPCH ...

Cardiovascular Research, Original Article, Shijie Cai, Nicholas J Alp, Denise McDonald, Ian Smith, Jonathan Kay, Laura Canevari, Simon Heales, Keith M Channon

Date : 01/09/2002
Ehjcardiovascrec

Abstract Objective:: Endothelial dysfunction in diabetes is characterized by decreased nitric oxide (NO) bioactivity and increased superoxide (SO) production. Methods: After 5 days, the cells ...

Cardiovascular Research, Research Article, Shijie Cai, Jeffrey Khoo, Keith M. Channon

Date : 01/03/2005
Ehjcardiovascrec

Abstract Objective: Previous studies from our group have shown a deficit in nitric oxide (NO) bioavailability and an excess production of the superoxide anion (O2 in the stroke prone spontaneously ...

Cardiovascular Research, Original Article, M.Yvonne Alexander, M.Julia Brosnan, Carlene A. Hamilton, Jérôme P. Fennell, Elisabeth C. Beattie, Emma Jardine, Donald D. Heistad, Anna F. Dominiczak

Date : 18/08/2000
Ehjcardiovascrec

Recent studies in angiotension II-induced hypertension [6] and in the stroke-prone spontaneously hypertensive rat (SHRSP) [7,8], suggest that an increased production of the superoxide anion (O2 could ...

Cardiovascular Research, Alexander, M.Yvonne, Brosnan, M.Julia, Hamilton, Carlene A., Fennell, Jérôme P., Beattie, Elisabeth C., Jardine, Emma, Heistad, Donald D., Dominiczak, Anna F.

Date : 18/08/2000 Item size : 304364 bytes
Ehjcardiovascrec

Abstract Objective:: Endothelial dysfunction in diabetes is characterized by decreased nitric oxide (NO) bioactivity and increased superoxide (SO) production. Methods: After 5 days, the cells ...

Cardiovascular Research, Cai, Shijie, Khoo, Jeffrey, Channon, Keith M.

Date : 01/03/2005
Ehjcardiovascrec

Abstract Objective: We have shown previously that there is a relative nitric oxide deficiency at the level of vascular endothelium in the stroke-prone spontaneously hypertensive rat (SHRSP), a model ...

Cardiovascular Research, Alexander, M.Yvonne, Brosnan, M.Julia, Hamilton, Carlene A, Downie, Paul, Devlin, Alison M, Dowell, Fiona, Martin, William, Prentice, Howard M, O’Brien, Timothy, ...

Date : 15/08/1999
Ehjcardiovascrec

GTP cyclohydrolase I gene transfer augments intracellular tetrahydrobiopterin in human endothelial cells: effects on nitric oxide synthase activity, protein levels and dimerisation Results: GTPCH ...

Cardiovascular Research, Cai, Shijie, Alp, Nicholas J, McDonald, Denise, Smith, Ian, Kay, Jonathan, Canevari, Laura, Heales, Simon, Channon, Keith M

Date : 01/09/2002 Item size : 295107 bytes
Ehjcardiovascrec

Reduced NO bioavailability, which is associated with an increase in the formation of reactive oxygen species within the vascular wall, is the key determinant of endothelial dysfunction. The ...

Cardiovascular Research, Bauersachs, Johann, Schäfer, Andreas

Date : 01/03/2005
Ehjcardiovascrec

Abstract Objective: We have shown previously that there is a relative nitric oxide deficiency at the level of vascular endothelium in the stroke-prone spontaneously hypertensive rat (SHRSP), a model ...

Cardiovascular Research, Alexander, M.Yvonne, Brosnan, M.Julia, Hamilton, Carlene A, Downie, Paul, Devlin, Alison M, Dowell, Fiona, Martin, William, Prentice, Howard M, O’Brien, Timothy, ...

Date : 15/08/1999