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[...]there is some evidence that the UPS itself modulates the activity of endothelial nitric oxide synthase, the key enzyme of vascular homeostasis, interacts with other vasoactive mediators involved ...

Cardiovascular Research, Review, Karl Stangl, Verena Stangl

Date : 15/01/2010 Item size : 509363 bytes

In order to investigate the existence of potential gender differences on the effects of intrauterine undernutrition, both male and female offspring of pregnant Wistar rats on normal and restricted ...

Cardiovascular Research, Original Article, Maria do Carmo P Franco, Robéria Maria M.P Arruda, Ana Paula Villela Dantas, Elisa Mitiko Kawamoto, Zuleica B Fortes, Cristoforo Scavone, Maria Helena C ...

Date : 01/10/2002 Item size : 250179 bytes

Rapamycin also impaired cell mobility, as assessed by a wound test, and promoted the formation of actin stress fibres, as determined with confocal microscopy. [...]the inhibitor prolonged ...

Cardiovascular Research, Original Article, Amelia Barilli, Rossana Visigalli, Roberto Sala, Gian C. Gazzola, Alessandro Parolari, Elena Tremoli, Sabrina Bonomini, Alexandra Simon, Ellen I. Closs, ...

Date : 01/06/2008 Item size : 295259 bytes

[...]Ca2+ influx may stimulate the activity of a constitutive nitric oxide synthase, which catalyses the production of nitric oxide (NO).1 Ca2+ entry may also activate phospholipase A2, a key enzyme ...

Cardiovascular Research, Original Article, Jun-Hao Huang, Guo-Wei He, Hong-Mei Xue, Xiao-Qiang Yao, Xiao-Cheng Liu, Malcolm John Underwood, Qin Yang

Date : 01/08/2011 Item size : 303330 bytes

Abstract Objective: We have shown previously that there is a relative nitric oxide deficiency at the level of vascular endothelium in the stroke-prone spontaneously hypertensive rat (SHRSP), a model ...

Cardiovascular Research, Original Article, M.Yvonne Alexander, M.Julia Brosnan, Carlene A Hamilton, Paul Downie, Alison M Devlin, Fiona Dowell, William Martin, Howard M Prentice, Timothy ...

Date : 15/08/1999 Item size : 290659 bytes

Professor Patrick Vallance BHF Laboratories, Division of Medicine, University College London, London W1P 9LN, UK; In 1980 Furchgott and Zawadzki described the phenomenon of ...

Heart, Mini-symposium, P Vallance

Date : 01/10/2005

There is evidence that as the endothelium ages, it is exposed to the damaging effects of raised blood pressure and increased concentrations of cholesterol, glucose, homocysteine, to products of the ...

Heart, Mini-symposium, L C Jones, A D Hingorani

Date : 01/10/2005

Dr Dimitris Tousoulis Athens University Medical School, S Karagiorga Street 69, 166 75, Glifada, Athens, Greece; The endothelium regulates vascular homeostasis through the release ...

Heart, Education in Heart, D Tousoulis, C Antoniades, C Stefanadis

Date : 01/04/2005

Tel: +44 121 5075080, Fax: +44 121 554 4083, Email: Search for more papers by this author Wrigley Benjamin J., University of Birmingham Centre for Cardiovascular Sciences, City ...

European Journal of Heart Failure, Shantsila, Eduard, Wrigley, Benjamin J., Blann, Andrew D., Gill, Paramjit S., Lip, Gregory Y.H.

Date : 01/08/2012 Item size : 202684 bytes

Abstract Aims Hazardous environmental and genetic factors can damage endothelial cells to induce atherosclerotic vascular disease. Methods and results Human umbilical vein endothelial cells (HUVECs) ...

Cardiovascular Research, Original Article, Qing-jun Zhang, Zhao Wang, Hou-zao Chen, Shuang Zhou, Wei Zheng, Guang Liu, Yu-sheng Wei, Hua Cai, De-pei Liu, Chih-chuan Liang

Date : 01/11/2008 Item size : 255240 bytes